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Blobel Laboratory Publications

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Below is a list of publications from the Blobel Laboratory

Molecular basis of polycomb group protein-mediated fetal hemoglobin repression
Blood · June, 2023
Gene silencing dynamics are modulated by transiently active regulatory elements
Molecular Cell · March, 2023
Identification and characterization of RBM12 as a novel regulator of fetal hemoglobin expression
Blood Advances · December, 2022
CTCF blocks antisense transcription initiation at divergent promoters
Nature Structural & Molecular Biology · November, 2022
Targeting the EIF2AK1 Signaling Pathway Rescues Red Blood Cell Production in SF3B1-Mutant Myelodysplastic Syndromes With Ringed Sideroblasts
Blood Cancer Discovery · November, 2022
HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription
Nature Genetics · September, 2022
Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells
Nature Genetics · June, 2022
CTCF and transcription influence chromatin structure re-configuration after mitosis
Nat Commun · August, 2021
Distinct properties and functions of CTCF revealed by a rapidly inducible degron system
Cell Reports · February, 2021
ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression
Molecular Cell · January, 2021
Alteration of genome folding via engineered boundary insertion
Nature Genetics · August, 2020
Understanding heterogeneity of fetal hemoglobin induction through comparative analysis of F and A erythroblasts
Blood · May, 2020
Chromatin structure dynamics during the mitosis-to-G1 phase transition
Nature · December, 2019
Interrogating Histone Acetylation and BRD4 as Mitotic Bookmarks of Transcription
Cell Rep · April, 2019
Transcriptional Burst Initiation and Polymerase Pause Release Are Key Control Points of Transcriptional Regulation
Molecular Cell · February, 2019
Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells
Science · July, 2018
Exploiting genetic variation to uncover rules of transcription factor binding and chromatin accessibility
Nature Communications · February, 2018
The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries
Mol Cell · April, 2017