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Results for Epigenetics

1 - 10 of 90

Kathleen E. Sullivan, MD, PhD
Photo of Kathleen E. Sullivan

Dr. Sullivan's research focuses on new and rare immunodeficiencies. She has a long-standing interest in one of the most common of the primary immunodeficiencies – chromosome 22q11.2 deletion syndrome. She also investigates common variable immunodeficiency, as well as the genetics and epigenetics of systemic lupus erythematosus.

E-mail:
sullivank [at] chop.edu
Jennifer M. Kalish, MD, PhD
Jennifer M. Kalish

Dr. Kalish's research focuses on understanding the molecular and epigenetic mechanisms that contribute to the predisposition to cancer that is characteristic of pediatric patients with rare imprinted gene disorders, including the overgrowth disorder Beckwith-Wiedemann syndrome (BWS).

E-mail:
kalishj [at] chop.edu
Colin Conine, PhD
Colin C. Conine

Dr. Conine works to understand the functions of small RNAs in reproduction, epigenetic inheritance, and development. His research focuses on how small RNAs in sperm transmit epigenetic information to offspring, as well as their involvement in male fertility.

E-mail:
conine [at] chop.edu
Andrew D. Wells, PhD
Andrew D. Wells

Dr. Wells studies the genetic, epigenetic, and transcriptional mechanisms that control T lymphocyte immunity and tolerance.

E-mail:
wellsa [at] chop.edu
Gerd Blobel, MD, PhD
Gerd Blobel

Dr. Blobel investigates the fundamental mechanisms involving transcription factors, chromatin regulators, and higher order chromatin. He is gearing his basic science discoveries towards genetic and epigenetic treatment modalities. In addition, Dr. Blobel is interested in mechanism of epigenetic memory.

E-mail:
blobel [at] chop.edu
Wanding Zhou, PhD
Wanding Zhou

Dr. Zhou’s outstanding research interests include mitosis-coupled DNA methylation drift and inference of cell-type-specific epigenetic signals. He developed multiple computational tools for analyzing DNA methylation data and has actively contributed to cancer genomics data analysis.

E-mail:
zhouw3 [at] chop.edu
Ana G. Cristancho, MD, PhD
Ana G. Cristancho

Dr. Cristancho is a child neurologist specializing in Fetal and Neonatal Neurology. Her research focuses on understanding the mechanisms that regulate the extent of disabilities some kids have after prenatal and neonatal brain injury. Her goal is to help develop novel therapeutic interventions.

E-mail:
cristanchoa [at] chop.edu
Will Bailis, PhD
Will Bailis

Dr. Bailis aims to understand how metabolism underlies immunology and disease, by controlling the biochemistry of cells and tissues. His lab does so using in vitro and in vivo CRISPR engineering of primary human and mouse immune cells, with the goal of developing diet and metabolite based therapies.

E-mail:
bailisw [at] chop.edu
Evan Weber, PhD
Evan W. Weber

Dr. Weber is developing approaches to enhance CAR-T cell therapies for pediatric cancer by reprogramming T cells with improved durability and exhaustion resistance. His work will uncover molecular mechanisms that promote CAR-T cell exhaustion and identify new targets for therapeutic intervention.

E-mail:
weberew [at] chop.edu
David A. Hill, MD, PhD
David A. Hill

Dr. Hill seeks to understand how the immune system contributes to the two most common chronic diseases of childhood: allergy and obesity. He uses clinical and epidemiological information to guide basic and translational research on the genetic, epigenetic, and immunologic basis of these important conditions.

E-mail:
hilllab [at] chop.edu
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In this section

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  • Principal Investigator / Faculty (15)

Organizations

  • Department of Biomedical and Health Informatics (8)
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  • Division of Allergy and Immunology (6)
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  • Center for Mitochondrial and Epigenomic Medicine (4)
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  • Akizu Laboratory (2)
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  • Wells Laboratory (2)
  • Advancement of Hyperinsulinism Care and Research (1)
  • Bailis Laboratory (1)
  • Bhoj Laboratory (1)
  • Brain-Gene-Development Lab (1)
  • Cancer Immunotherapy (CAR-T) (1)
  • Center for Pediatric Clinical Effectiveness (1)
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  • Department of Radiology (1)
  • Division of Adolescent Medicine (1)
  • Division of Endocrinology and Diabetes (1)
  • Division of Gastroenterology, Hepatology, and Nutrition (1)
  • Division of Hematology (1)
  • Fetal Biology and Therapy Research Affinity Group (1)
  • Food Allergy Center (1)
  • Friedreich’s Ataxia Center of Excellence (1)
  • Hill Laboratory (1)
  • IDDRC Neuroimaging and Neurocircuitry Core (1)
  • Jill and Mark Fishman Center for Lymphatic Disorders (1)
  • Kilbaugh Laboratory (1)
  • Minds Matter Concussion Program (1)
  • Normal and Malignant Hematopoiesis Research Affinity Group (1)
  • PolicyLab (1)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (1)
  • Spatial and Functional Genomics Collaborative (1)

In this section

Filter By

  • Principal Investigator / Faculty (15)

Organizations

  • Department of Biomedical and Health Informatics (8)
  • Department of Pediatrics (7)
  • Division of Allergy and Immunology (6)
  • Center for Computational and Genomic Medicine (4)
  • Center for Mitochondrial and Epigenomic Medicine (4)
  • Division of Human Genetics (4)
  • Blobel Laboratory (3)
  • Center for Applied Genomics (3)
  • Center for Autism Research (3)
  • Center for Childhood Cancer Research (3)
  • Division of Oncology (3)
  • Akizu Laboratory (2)
  • Beckwith-Wiedemann Syndrome Program of Excellence (2)
  • Center for Data-Driven Discovery in Biomedicine (2)
  • Center for Injury Research and Prevention (2)
  • Children’s Oncology Group (2)
  • Department of Anesthesiology and Critical Care Medicine (2)
  • Department of Pathology and Laboratory Medicine (2)
  • Division of Infectious Diseases (2)
  • Division of Neonatology (2)
  • Division of Neurology (2)
  • Grant Laboratory (2)
  • Lifespan Brain Institute (2)
  • Office of Academic Training and Outreach Programs (2)
  • Roberts Individualized Medical Genetics Center (2)
  • Spatial and Functional Genomics Research Affinity Group (2)
  • Wells Laboratory (2)
  • Advancement of Hyperinsulinism Care and Research (1)
  • Bailis Laboratory (1)
  • Bhoj Laboratory (1)
  • Brain-Gene-Development Lab (1)
  • Cancer Immunotherapy (CAR-T) (1)
  • Center for Pediatric Clinical Effectiveness (1)
  • Computational Epigenetics (1)
  • Department of Child and Adolescent Psychiatry and Behavioral Sciences (1)
  • Department of Radiology (1)
  • Division of Adolescent Medicine (1)
  • Division of Endocrinology and Diabetes (1)
  • Division of Gastroenterology, Hepatology, and Nutrition (1)
  • Division of Hematology (1)
  • Fetal Biology and Therapy Research Affinity Group (1)
  • Food Allergy Center (1)
  • Friedreich’s Ataxia Center of Excellence (1)
  • Hill Laboratory (1)
  • IDDRC Neuroimaging and Neurocircuitry Core (1)
  • Jill and Mark Fishman Center for Lymphatic Disorders (1)
  • Kilbaugh Laboratory (1)
  • Minds Matter Concussion Program (1)
  • Normal and Malignant Hematopoiesis Research Affinity Group (1)
  • PolicyLab (1)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (1)
  • Spatial and Functional Genomics Collaborative (1)
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