Division of Gastroenterology, Hepatology, and Nutrition Research Studies

The purpose of this research study is to collect different types of samples (such as stool, swabs, urine) to form a biorepository.

CAPTURE Inflammatory Bowel Disease (IBD) is a multi-center, longitudinal study designed with the goal of advancing precision medicine in pediatric IBD.

Children's Hospital of Philadelphia (CHOP) is inviting healthy individuals ages 0-21 to become part of a unique opportunity to help other kids heal: the CHOP Pediatric Fecal Microbiota Transplant (FMT) Stool Bank.

The purpose of this study is to assess the efficacy, safety, and how the body interacts with an investigational drug in pediatric patients with Crohn's disease who have not had success with other medications.

This study seeks to characterize dietary intake in children with or without IBS and explore severity of symptoms and quality of life.

Evaluate the impact of non-persistent and persistent chemical exposures on autoimmunity, gene expression and the microbiome in children with and without Crohn’s disease.

The University of Pennsylvania, in collaboration with CHOP, is conducting a study to find out more about how behaviors (eating, physical activity, sleep) and genes affect growth and development in children.

Gastrointestinal motility disorders (GMD) and disorders of gut brain interactions (DGBI) include a wide spectrum of disease conditions, and it's relatively common in the general population.

Teens ages 14-17 with BMI in the 85th percentile or above and without diabetes are invited to participate in the HEALTHY BITES Research Study.

A new, safe, state-of-the-art technique called HR-pQCT (high resolution peripheral quantitative computed tomography) can be used to measure bone health in children and adults.

A research study about bone health in children and adolescents at high risk of suffering a broken bone.

The purpose of this study is to help children who are tube-fed transition to eating orally.

The study aims to understand which genes cause IBD and expand on what is known about how IBD affects those with African ancestry.

The purpose of this study is to find out if myofascial release therapy (MFR), (a massage method that will be used in the belly area), will improve the symptoms in CHOP patients with Irritable Bowel Syndrome (IBS).

The purpose of this study is to help understand how well new IBD medications work, obtain safety information, and understand patient's quality of life while on the medications.

Inflammatory Bowel Disease (IBD) can sometimes add stress to your life and that may affect your physical symptoms of pain and stool habits. In this study, we want to know if practicing mindfulness via an online Mindfulness-based stress reduction (MBSR) course taught by a trained teacher can help with your IBD.

This is an open-label, Phase 3 clinical trial evaluating the efficacy of Tofacitinib based on remission in children with moderate to severe ulcerative colitis.

The purpose of this study is to characterize the microbiome in children with Crohn's disease who have perianal fistula and to compare it to other children with Crohn's disease who do not have perianal disease.

Kids with IBD (inflammatory bowel disease) often struggle with tiredness and difficulty doing everyday activities, which can make life harder, but there aren't good tools to measure these problems in children.

The goals of this research study are to learn more about acute recurrent and chronic pancreatitis in order to better understand the disease in the hopes of enhancing future treatment options.

This study was designed to measure components or metabolites of PEG 3350 in blood and urine from children who were already taking PEG 3350 and to compare these levels to measurements of the same molecules from a group of children who were not taking PEG 3350.

The RE-EEN Smoothie Study is recruiting patients newly diagnosed with Crohn's Disease who are interested in using diet to help achieve disease remission.

The Children’s Hospital of Philadelphia is seeking healthy adolescents between the ages of 12-13, who are currently in the 7^th grade, to participate in the Sleep and Growth Study 2. 

The goal of this study is to find out if we can develop a digital health approach that can increase sleep duration and improve growth outcomes in children.

The purpose of this research study is to help us understand how well tofacitinib works as a treatment for ulcerative colitis or indeterminate colitis in pediatric patients.

The purpose of this research study is to identify genes that are involved in the development of Inflammatory Bowel Disease (IBD) at a young age (less than 8 years of age).

This study aims to evaluate how Risankizumab, a medication used to treat Crohn's Disease, works in children.