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The purpose of this investigation is to evaluate the impact of non-persistent and persistent chemical exposures on autoimmunity, gene expression and the microbiome in children with and without Crohn’s disease. If these chemical exposures are associated with differences in the epigenome and microbiome that are known to predispose for Crohn’s disease, the proposed research could further support changes in dietary behaviors to limit exposure, and efforts to regulate manufacturing processes that unintentionally and intentionally add these chemicals to food.

Who Do I Contact?

If you are interested in participating in the study or want to learn more please contact our study team at ibdresearch [at] chop.edu or 267-426-0417.

Eligibility & Criteria

IRB #:
22-020141
Official Title:
Identifying Environmental Contributors to Crohn's Disease
Study Phase:
Not Applicable
Eligible Age Range:
6 - 25 Years
Gender:
All
Study Categories:

Visit Criteria

Participants will have two (2) study visits which will coincide with regular clinical visits. The second study visit will occur six (6) months after the first.
Visits will include medical record review, completion of questionnaires, blood, stool, urine and saliva sample collection.