Results for Inflammatory Bowel Disease

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Dr. Grossman is a pediatric gastroenterologist and co-director of Children's Hospital of Philadelphia’s Center for Pediatric Inflammatory Bowel Disease.

E-mail:

grossmanan [at] chop.edu

Judith R. Kelsen, MD

Dr. Kelsen’s research focus is on the genetic, immunologic, and microbiomic causes of very early onset inflammatory bowel disease. Through a multidisciplinary team approach, Dr. Kelsen and her colleagues perform genetic sequencing to identify causative genetic variants in children with VEO-IBD, study the function of these variants, and use this information to improve the clinical outcomes for these children.

E-mail:

kelsen [at] chop.edu

Robert N. Baldassano, MD

Dr. Baldassano’s research focuses on children who have inflammatory bowel diseases, and he oversees a large team of researchers at CHOP working to translate discoveries in the laboratory into direct patient care for children. One promising area of current research involves investigating the intestinal microbiomes of children with inflammatory bowel diseases.

E-mail:

baldassano [at] chop.edu

Kathryn E. Hamilton, PhD

Dr. Hamilton studies intestinal epithelial cells and how they help maintain human health. Although there is a great deal understood about how these cells function, little is known about how they behave during disease. Dr. Hamilton focuses on defining new mechanisms in regenerative medicine, inflammatory bowel disease, and colorectal cancer.

E-mail:

hamiltonk1 [at] chop.edu

David A. Piccoli, MD

In addition to serving as chief of the Division of Gastroenterology, Hepatology, and Nutrition, Dr. Piccoli pursues research about metabolic and genetic liver disease, inflammatory bowel disease, and rare gastrointestinal disorders. He is a member of the group that discovered Jagged1 and NOTCH2 as the primary causes of Alagille syndrome.

E-mail:

piccoli [at] chop.edu

Louis R. Ghanem, MD, PhD

Dr. Ghanem investigates the impact of transcriptional gene expression controls and mRNA processing upon the severity and progression of pediatric inflammatory bowel disease.

E-mail:

ghaneml [at] chop.edu

Christopher J. Cardinale, MD, PhD

Dr. Cardinale's research is focused on understanding the mechanisms of gene expression and gene regulation in autoimmune diseases, including inflammatory bowel disease, type 1 diabetes, and systemic sclerosis. He uses data from large-scale genomic studies to identify disease-causing genetic variants and functionally explore the target genes of those variants.

E-mail:

cardinalec [at] chop.edu

Peter Mattei, MD

Dr. Mattei is an attending physician in the Division of General, Thoracic and Fetal Surgery and specializes in pediatric surgical oncology, inflammatory bowel disease, and minimally invasive and robotic surgery. His research interests are in oncology and IBD.

E-mail:

mattei [at] chop.edu

Kathleen E. Sullivan, MD, PhD

Dr. Sullivan's research focuses on new and rare immunodeficiencies. She has a long-standing interest in one of the most common of the primary immunodeficiencies – chromosome 22q11.2 deletion syndrome. She also investigates common variable immunodeficiency, as well as the genetics and epigenetics of systemic lupus erythematosus.

E-mail:

sullivank [at] chop.edu

Michael S. Marks, PhD

Dr. Marks investigates the molecular mechanisms underlying the formation of cell type-specific lysosome-related organelles; the assembly, delivery and function of their contents; and how these processes are impacted by genetic diseases.

E-mail:

marksms [at] chop.edu