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Transgenic Core
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The Transgenic Core provides investigators with state-of-the-art experimental models to study human disease, advance research, and propel discovery. Our expertise and capabilities enable us to build complex disease models using a combination of cutting-edge and classical genetic engineering approaches. The Transgenic Core has successfully created more than 100 transgenic lines using the CRISPR system and recently created our first CRISPR knockout line.
Our Core offers fast, cost-effective generation and preservation of transgenic lines with the following services:
- CRISPR Cas9 mRNA microinjection
- CRISPR Cas9 RNP electroporation
- DNA construct microinjection
- Embryonic stem cell microinjection
- Strain rederivation and rescue
- Embryo cryopreservation, importation, and exportation
- Sperm cryopreservation, importation, and exportation.
A variety of innovative equipment enhances the level of the Transgenic Core services in further support of your research projects. Visit our Getting Started page for first steps and FAQs.
Work with Us! Let us show you how we can help you to conduct efficient, cost-effective transgenic and gene-targeting research. Contact the Transgenic Core team for a consultation.