Results for Import

Dr. Katz’s investigates the sequelae of obesity and type 2 diabetes mellitus in youth. Her research involves the intersection of sleep, obesity, and glucose intolerance and prevention of cardiovascular risk. Her studies have led to the evaluation of quantitative tools important for assessment of metabolic risk in youth.

Dr. Getz develops and applies advanced methods to enable epidemiologic research that aims to optimize the treatment and supportive care of children with cancer by balancing the therapeutic benefits and toxicity risks with an emphasis in cardio-oncology.

Dr. Dowshen focuses on improving the health outcomes for adolescent and young adults (AYA) living with or at high risk for contracting HIV/AIDS and improving access and quality of care for gender expansive and transgender children and adolescents. She is particularly interested in developing and testing digital health interventions to reach, engage, and retain AYA in care.

Dr. Stanley’s lab has identified many of the genes and syndromes associated with congenital hyperinsulinism including ABCC8, GCK, GLUD1, and Turner and Beckwith syndromes. Working with clinical and rodent model studies, his lab team has identified distinctive phenotypes of these disorders, including diazoxide unresponsiveness, leucine sensitivity, and protein sensitivity. Dr. Stanley continues to seek new diagnostic and treatment paradigms for infants with acquired and genetic disorders of hyperinsulinism.

Dr. Gonzalez-Alegre's long-range research goal is to advance the application of precision medicine in the neurology clinic. His research focus revolves around genetic disorders that affect the brain, spanning from the diagnosis of novel genetic disease in the clinic to the identification of novel molecular targets using disease models and the design of early-phase human clinical trials.

Dr. Rossano's extensive research experience primarily involves the epidemiology and outcomes of cardiovascular disease in children, and multi-institutional collaborative observational and interventional studies. His particular research interests include evaluating the treatment and outcomes of pediatric cardiomyopathy, heart failure, and transplantation.

Dr. Spinner's research focuses on the etiology and expressivity of pediatric developmental disorders. She uses genomic methods to focus on the multisystem disorder Alagille syndrome and biliary atresia, a likely heterogeneous and poorly understood condition. She is also interested in using genomic tools to continue to improve diagnostic rates for constitutional genetic disorders.

Dr. De Leon-Crutchlow’s translational research program focuses on examining the pathophysiology of disorders of insulin regulation, identifying novel therapeutic targets, and developing new therapies for these conditions. The program approach includes patient-oriented research and bench research employing mouse models and primary islet cultures.

Narasaiah Kovuru’s research focuses on understanding the origins of hematopoietic failure/bone marrow failure in Fanconi Anemia working with the murine model.