In This Section

Melanie A. Ruffner, MD, PhD
Melanie A. Ruffner
Attending Physician

Classic food allergies are mediated through immunoglobulin E and manifest as hives, vomiting, and anaphylaxis. Dr. Ruffner investigates the immune mechanisms of food allergy disorders which are not mediated through immunoglobulin E. In particular, the mechanisms of eosinophilic esophagitis and food-protein induced enterocolitis syndrome are of particular interest in Dr. Ruffner's laboratory.



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Education and Training

BS, Johns Hopkins University (Biomedical Engineering), 2003

PhD, University of Pittsburgh (Bioengineering), 2009

MD, University of Pittsburgh School of Medicine, 2011

Pediatrics Residency, Children’s Hospital of Philadelphia 2014

Fellowship, Children's Hospital of Philadelphia (Allergy and Immunology), 2017

MTR, University of Pennsylvania, 2020

Titles and Academic Titles

Attending Physician

Assistant Professor

Professional Memberships

American Association of Pediatrics

American Academy of Allergy, Asthma & Immunology

American College of Allergy, Asthma & Immunology

Clinical Immunology Society

Federation of Clinical Immunology Societies

Pennsylvania Allergy & Asthma Association

Professional Awards

American Academy of Allergy, Asthma and Immunology Chrysalis Award, 2011

American College of Allergy, Asthma and Immunology Young Faculty Award, 2016

American College of Allergy, Asthma and Immunology Young Faculty Development Award 2021

Publication Highlights