Hematopoietic Stem Cells | CHOP Research Institute
 

Hematopoietic Stem Cells

This study is enrolling people who have developed lung problems (called Bronchiolitis Obliterans or BO) after hematopoietic stem cell transplant (HSCT).

Published on
Sep 13, 2024
Researchers evaluate psychological risk factors associated with post-concussion quality of life and more in this week’s news.
Published on
Jul 31, 2023
Researchers developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.
Published on
Sep 9, 2022
In this Q&A, hematologist Dr. Kwiatkowski discusses the Food and Drug Administration approval of beti-cel (Zynteglo®), a gene therapy for beta thalassemia.

The Tong laboratory studies cytokine receptor and ubiquitin signaling in hematopoietic stem cells, bone marrow failure, and leukemia.

The Rivella Laboratory uses lentiviral vectors for modulation of gene expression and gene transfer for the cure of hemoglobinopathies.

The Comprehensive Bone Marrow Failure Center brings together physicians and researchers to provide state-of-the-art diagnostics, clinical care, and investigational studies, as well as basic research focused on acquired and inherited bone marrow failure.

The Kurre Laboratory has a longstanding interest in Fanconi Anemia (FA), a genetic condition with prominent hematologic complications.

Dr. Tong investigates cytokine receptor signaling in normal and neoplastic hematopoietic development. She uses integrated approaches encompassing biochemistry, molecular biology, mouse models, and primary human samples to understand signaling events emanating from cytokine receptors that regulate the development of hematopoietic stem/progenitor cells.

E-mail:
tongw [at] chop.edu

Dr. Kurre's laboratory has longstanding expertise in Fanconi Anemia (FA), a genetic condition with prominent hematologic complications. With training in transplantation and hematopoietic stem cell biology, he hopes to improve the understanding of the progressive hematopoietic failure in patients with bone marrow failure and FA, broaden diagnostic approaches, and develop next generation therapies.

E-mail:
kurrep [at] chop.edu