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HillLab [at] email.chop.edu
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Room 1212

3615 Civic Center Blvd
Philadelphia, PA 19104
United States

Research Topics
David A. Hill, MD, PhD
David A. Hill
Attending Physician

Dr. Hill seeks to understand how the immune system contributes to the two most common chronic diseases of childhood: allergy and obesity. He uses clinical and epidemiological information to guide basic and translational research on the genetic, epigenetic, and immunologic basis of these important conditions.

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Bio

Dr. Hill is an assistant professor of Pediatrics in the Perelman School of Medicine at the University of Pennsylvania, and an attending physician in the Division of Allergy and Immunology at Children’s Hospital of Philadelphia. Dr. Hill received his undergraduate education at Carnegie Mellon University, and his MD and PhD from the University of Pennsylvania, where he trained with Dr. David Artis. He completed a pediatric residency and allergy and immunology fellowship at Children’s Hospital of Philadelphia, during which time he performed post-doctoral research under the mentorship of Drs. Jonathan Spergel and Mitchell Lazar. Dr. Hill runs a basic and translational research lab that studies the role of the immune system in pediatric allergy and obesity

Among his notable career achievements so far, Dr. Hill received the:

  • Clemens Von Pirquet Award from the American College of Allergy, Asthma & Immunology in 2017
  • Mentored Clinical Scientist Research Career Development Award from the National Institute of Diabetes and Digestive and Kidney Diseases in 2018
  • Children's Hospital of Philadelphia Distinguished Research Trainee Award in 2019

Education and Training

BS, Carnegie Mellon University (Biological Sciences), 2005

PhD, University of Pennsylvania (Immunology), 2011

MD, University of Pennsylvania, 2013

Residency, Children's Hospital of Philadelphia (Pediatrics), 2016

Fellowship, Children's Hospital of Philadelphia (Allergy and Immunology), 2018

Titles and Academic Titles

Attending Physician

Assistant Professor of Pediatrics

Professional Memberships

American Academy of Pediatrics, 2013-

American College of Allergy, Asthma and Immunology, 2016-

American Academy of Allergy, Asthma and Immunology, 2016-

World Allergy Organization, 2017-

American Heart Association, 2019-

Professional Awards

Section on Allergy & Immunology Award, American Academy of Pediatrics, 2014

Chrysalis Award, American Academy of Allergy, Asthma & Immunology, 2014

Outstanding Pediatric Abstract Award, AAAAI AAP Section on Allergy and Immunology, 2016

Senior Resident Research Award, Children’s Hospital of Philadelphia, 2016

Award for Outstanding Patient-Oriented Research, Children’s Hospital of Philadelphia Research Symposium, 2016

Clemens Von Pirquet Award, American College of Allergy, Asthma & Immunology, 2016

Award for Outstanding Patient-Oriented Research, Children’s Hospital of Philadelphia Research Symposium, 2017

Clemens Von Pirquet Award, ACAAI, 2017

Outstanding Pediatric Abstract Award, AAAAI AAP Section on Allergy and Immunology, 2018

Children's Hospital of Philadelphia Distinguished Research Trainee Award, 2019

American College of Allergy, Asthma, and Immunology Young Faculty Award, 2019

Publication Highlights

Hill DA, Grundmeier RW, Ramos M, Spergel JM. Eosinophilic esophagitis is a late manifestation of the allergic march. J Allergy Clin Immunol Pract. 2018 Jun; PMID: 29954692
Hill DA, Lim HW, Kim YH, Ho WY, Foong YH, Nelson VL, Nguyen HCB, Chegireddy K, Kim J, Habertheuer A, Vallabhajosyula P, Kambayashi T, Won KJ, Lazar MA. Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue. Proc Natl Acad Sci U S A. 2018 May; 115(22):E5096-E5105. PMID: 29760084. PMCID: PMC5984532
Hill DA, Grundmeier RW, Ram G, Spergel JM. The epidemiologic characteristics of healthcare provider-diagnosed eczema, asthma, allergic rhinitis, and food allergy in children: a retrospective cohort study. BMC Pediatr. 2016 Aug; 16:133. PMID: 27542726. PMCID: PMC4992234
Hill DA, Siracusa MC, Abt MC, Kim BK, Kobuley D, Kubo M, Kambayashi T, LaRosa DF, Renner ED, Orange JS, Bushman FD, Artis D. Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation. Nat Med. 2012 Mar; 18(4):538-46. PMID: 22447074. PMCID: PMC3321082
Hill DA, Hoffmann C, Abt MC, Du Y, Kobuley D, Kirn TJ, Bushman FD, Artis D. Metagenomic analyses reveal antibiotic-induced temporal and spatial changes in intestinal microbiota with associated alterations in immune cell homeostasis. Mucosal Immunol. 2010 Mar; 3(2):148-58. PMID: 19940845. PMCID: PMC2824244

Links of Interest

Getting in Step: Scientists Suggest Eosinophilic Esophagitis Part of Allergic March (June 25, 2018, Cornerstone blog)

Is Eosinophilic Esophagitis Part of the Allergic March? (July 6, 2018, Medscape Expert Commentary)

Addressing Disease Burden in Asthma: An Integrated View. (June 13, 2018, Medscape Spotlight Video)

Managing peanut allergy. (Nov. 9, 2017, Primary Care Perspectives: Podcast for Pediatricians)

Inner defenses against allergies. (April 2012 Nature Medicine Podcast)