HOW CAN WE HELP YOU? Call 1-800-TRY-CHOP
In This Section
Audrey R. Odom John, MD, PhD
Chief, Division of Infectious Diseases
Dr. John studies metabolism in the setting of pediatric infections, in order to identify new anti-infective drug targets, understand drug resistance, and develop new diagnostics.
Bio
A physician-scientist, Dr. John’s NIH-funded research focuses on microbial metabolism. Her translational studies aim to develop new diagnostics for malaria, SARS-CoV-2 infection, and MIS-C, and to develop new therapies for drug-resistant infections. Dr. John is an investigator in the Pathogenesis of Infectious Diseases of the Burroughs Welcome Fund. She has received numerous accolades, including awards from the American Chemical Society, March of Dimes, and the IDea Incubator Grand Prize from the Infectious Diseases Society of America.
Education and Training
BS, Duke University, (Biology, minor Chemistry), 1996
PhD, Duke University School of Medicine, (Biochemistry), 2002
MD, Duke University School of Medicine, 2002
Pediatric Residency (Special Alternative Pathway), University of Washington, 2003-2005
Pediatric Infectious Diseases Fellowship, University of Washington, 2005-2008
Titles and Academic Titles
Chief, Division of Infectious Diseases
Professor, Departments of Pediatrics and Microbiology
Perelman School of Medicine, University of Pennsylvania
Professional Memberships
Pediatric Infectious Diseases Society
Infectious Diseases Society of America
American Society of Microbiology
American Society of Tropical Medicine and Hygiene
Professional Awards
Doris Duke Charitable Foundation, Clinical Scientist Development Award, 2010
Innovator Award, St. Louis Academy of Science, 2012
Outstanding Commitment to Teaching Award, Washington University School of Medicine, Department of Pediatrics, 2013
Basil O’Connor Starter Scholar Award, March of Dimes, 2013
Election, Society for Pediatric Research, 2014
Grand challenge winner and invited speaker, TEDxKC, 2015
Emerging Leader Award, Duke University School of Medicine Alumni Association, 2016
Young Investigator Award, American Chemical Society – Infectious Diseases,
2016
Investigator in the Pathogenesis of Infectious Diseases, Burroughs Wellcome Fund, 2016
IDea Incubator Grand Prize winner, Infectious Diseases Society of America (IDSA), 2018
Election, American Pediatric Society, 2020
NIH/NICHD Director’s Award, 2021
Election, American Society of Clinical Investigation (ASCI), 2022
Pediatric Infectious Diseases Society, Women in Science Award, 2022
Publication Highlights
PubMed:
Elaina E. Lin, Elikplim H. Akaho, Anna Sobilo, Lisa R. Young, Rebecca M. Harris, Audrey R. Odom John. Concordance of Preprocedure Testing With Time-of-Surgery Testing for SARS-CoV-2 in Children. Pediatrics. 2021 Mar; e2020044289; DOI: 10.1542/peds.2020-044289
Mikati MO, Miller JJ, Osbourn DM, Barekatain Y, Ghebremichael N, Shah IT, Burnham CD, Heidel KM, Yan VC, Muller FL, Dowd CS, Edwards RL, Odom John AR. Antimicrobial Prodrug Activation by the Staphylococcal Glyoxalase GloB. ACS Infect Dis. 2020 Nov; 6(11):3064-3075. doi: 10.1021/acsinfecdis.0c00582. Epub 2020 Oct 29. PMID: 33118347
Guggisberg AM, Frasse PM, Jezewski AJ, Kafai NM, Gandhi AY, Erlinger SJ, Odom John AR. Suppression of Drug Resistance Reveals a Genetic Mechanism of Metabolic Plasticity in Malaria Parasites. mBio. 2018 Nov; pii: e01193-18. doi: 10.1128/mBio.01193-18. PMID: 30425143; PMCID: PMC6234871
Schaber CL, Katta N, Bollinger LB, Mwale M, Mlotha-Mitole R, Trehan I, Raman B, Odom John AR. Breathprinting Reveals Malaria-Associated Biomarkers and Mosquito Attractants. J Infect Dis. 2018 Apr; 217(10):1553-1560. doi: 10.1093/infdis/jiy072. PMID: 29415208
Guggisberg AM, Sundararaman SA, Lanaspa M, Moraleda C, González R, Mayor A, Cisteró P, Hutchinson D, Kremsner PG, Hahn BH, Bassat Q, Odom AR. Whole-Genome Sequencing to Evaluate the Resistance Landscape Following Antimalarial Treatment Failure With Fosmidomycin-Clindamycin. J Infect Dis. 2016 Oct; 214(7):1085-91. doi: 10.1093/infdis/jiw304. Epub 2016 Jul 20. PMID: 27443612, PMCID: PMC5021231