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Audrey R. Odom John, MD, PhD
Audrey R. Odom John, MD, PhD
Chief, Division of Infectious Diseases

Dr. John studies metabolism in the setting of pediatric infections, in order to identify new anti-infective drug targets, understand drug resistance, and develop new diagnostics.



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A physician-scientist, Dr. John’s NIH-funded research focuses on microbial metabolism. Her translational studies aim to develop new diagnostics for malaria, SARS-CoV-2 infection, and MIS-C, and to develop new therapies for drug-resistant infections. Dr. John is an investigator in the Pathogenesis of Infectious Diseases of the Burroughs Welcome Fund. She has received numerous accolades, including awards from the American Chemical Society, March of Dimes, and the IDea Incubator Grand Prize from the Infectious Diseases Society of America.

Education and Training

BS, Duke University, (Biology, minor Chemistry), 1996

PhD, Duke University School of Medicine, (Biochemistry), 2002

MD, Duke University School of Medicine, 2002

Pediatric Residency (Special Alternative Pathway), University of Washington, 2003-2005 

Pediatric Infectious Diseases Fellowship, University of Washington, 2005-2008

Titles and Academic Titles

Chief, Division of Infectious Diseases

Professor, Departments of Pediatrics and Microbiology

Perelman School of Medicine, University of Pennsylvania

Professional Memberships

Pediatric Infectious Diseases Society

Infectious Diseases Society of America

American Society of Microbiology

American Society of Tropical Medicine and Hygiene

Professional Awards

Doris Duke Charitable Foundation, Clinical Scientist Development Award, 2010

Innovator Award, St. Louis Academy of Science, 2012

Outstanding Commitment to Teaching Award, Washington University School of Medicine, Department of Pediatrics, 2013

Basil O’Connor Starter Scholar Award, March of Dimes, 2013

Election, Society for Pediatric Research, 2014

Grand challenge winner and invited speaker, TEDxKC, 2015

Emerging Leader Award, Duke University School of Medicine Alumni Association, 2016

Young Investigator Award, American Chemical Society – Infectious Diseases,

Investigator in the Pathogenesis of Infectious Diseases, Burroughs Wellcome Fund, 2016

IDea Incubator Grand Prize winner, Infectious Diseases Society of America (IDSA), 2018

Election, American Pediatric Society, 2020

NIH/NICHD Director’s Award, 2021

Election, American Society of Clinical Investigation (ASCI), 2022

Pediatric Infectious Diseases Society, Women in Science Award, 2022

Publication Highlights

Elaina E. Lin, Elikplim H. Akaho, Anna Sobilo, Lisa R. Young, Rebecca M. Harris, Audrey R. Odom John. Concordance of Preprocedure Testing With Time-of-Surgery Testing for SARS-CoV-2 in Children. Pediatrics. 2021 Mar; e2020044289; DOI: 10.1542/peds.2020-044289
Mikati MO, Miller JJ, Osbourn DM, Barekatain Y, Ghebremichael N, Shah IT, Burnham CD, Heidel KM, Yan VC, Muller FL, Dowd CS, Edwards RL, Odom John AR. Antimicrobial Prodrug Activation by the Staphylococcal Glyoxalase GloB. ACS Infect Dis. 2020 Nov; 6(11):3064-3075. doi: 10.1021/acsinfecdis.0c00582. Epub 2020 Oct 29. PMID: 33118347
Guggisberg AM, Frasse PM, Jezewski AJ, Kafai NM, Gandhi AY, Erlinger SJ, Odom John AR. Suppression of Drug Resistance Reveals a Genetic Mechanism of Metabolic Plasticity in Malaria Parasites. mBio. 2018 Nov; pii: e01193-18. doi: 10.1128/mBio.01193-18. PMID: 30425143; PMCID: PMC6234871
Schaber CL, Katta N, Bollinger LB, Mwale M, Mlotha-Mitole R, Trehan I, Raman B, Odom John AR. Breathprinting Reveals Malaria-Associated Biomarkers and Mosquito Attractants. J Infect Dis. 2018 Apr; 217(10):1553-1560. doi: 10.1093/infdis/jiy072. PMID: 29415208
Guggisberg AM, Sundararaman SA, Lanaspa M, Moraleda C, González R, Mayor A, Cisteró P, Hutchinson D, Kremsner PG, Hahn BH, Bassat Q, Odom AR. Whole-Genome Sequencing to Evaluate the Resistance Landscape Following Antimalarial Treatment Failure With Fosmidomycin-Clindamycin. J Infect Dis. 2016 Oct; 214(7):1085-91. doi: 10.1093/infdis/jiw304. Epub 2016 Jul 20. PMID: 27443612, PMCID: PMC5021231

Links of Interest