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Advanced Personalized Therapeutics and Precision Surgery in Childhood Cancers
Children's Hospital of Philadelphia is positioned as a leader in cancer precision medicine, with highly integrated research and clinical programs. The Advanced Personalized Therapeutics and Precision Surgery in Childhood Cancers Frontier Program will further develop this work to create a destination precision medicine program enabled by novel tumor profiling assays. These include leukemia and solid tumor functional profiling and the first intraoperative methylation profiling available in the United States.
This frontier program will expand the proportion of patients with relapsed and refractory cancer for whom precision therapies are identified. The team will also leverage existing data alongside additional research sequencing and proteomic profiling to identify novel cell therapy targets for pediatric cancer. Novel collaboration will lead to transformative progress including:
The Advanced Personalized Therapeutics and Precision Surgery Program in Childhood Cancers is aiming to transform care for patients.
This multidisciplinary effort brings together CHOP's renowned cell therapy and precision medicine programs:
- Center for Data-Driven Discovery in Biomedicine
- Department of Surgery
- Department of Pathology and Laboratory Medicine
- Department of Pediatrics
The Frontier will establish new research collaborations to drive transformative clinical care based on research discoveries at CHOP and the University of Pennsylvania.
Cornerstone Blog
The Center for Precision Medicine for High-risk Pediatric Cancer Frontier Program builds upon ongoing precision medicine efforts across CHOP departments to define and expand treatment options.
Cornerstone Blog
Up to $10 million in funding will allow investigators from the Center for Data-Driven Discovery in Biomedicine to develop a new cloud-based toolkit for accessible data sharing.
Cornerstone Blog
With funding from the National Cancer Institute’s Childhood Cancer Data Initiative, CHOP researchers are identifying new immunotherapy targets.