CHOP researchers are developing a tool to illuminate brain activity in children with severe neurodevelopmental disorders, who are often excluded from research.
The Center for Brain Research in Development, Genetics and Engineering (BRIDGE) applies innovative technology and advanced model systems to understand basic mechanisms of brain development and advance the implementation of novel therapeutics.
The Cristancho Lab is interested in understanding the epigenetic mechanisms driving long-term neurodevelopmental disabilities from acquired prenatal and perinatal brain injury. Our goal is to develop novel therapies that can be used throughout the lifespan to improve outcomes for children.
Dr. Gandal investigates the genetic contributions to typical human brain development and neurodevelopmental and psychiatric disorders. His multidisciplinary research program integrates genetics with functional genomic profiling in the human brain, along with bioinformatics and computational biology.
Dr. Stephenson is an attending pediatric neurologist and medical director of Operations and Outreach for the Division of Neurology at CHOP. She has special interest in neurobehavioral and neurodevelopmental disorders including ADHD, autism, Tourette syndrome, learning disabilities, and developmental delay.