Autoimmune Disease | CHOP Research Institute
 

Autoimmune Disease

The ENERGY study is for adults (ages 18 and up) with warm Autoimmune Hemolytic Anemia (wAIHA) who are currently receiving treatment or have previously received treatment. The goal of the study is to see if the study drug, Nipocalimab is safe and effective in the treatment of wAIHA.

The Dova study is for children below 18 years with primary Immune Thrombocytopenia (ITP) who have had an insufficient response to previous treatment.

The Romberg Lab investigates the regulatory mechanisms enabling immune systems to fight infections without injuring ourselves. The lab is particularly interested in the immune system of primary immunodeficiency patients who are susceptible to both life-threatening infections and autoimmune diseases.

The Oliver Lab focuses on revealing mechanisms governing T cell activation and protective immunity. Its goal is to define mechanisms that, when dysregulated, result in autoimmunity or allergic disorders like asthma.

Published on
Dec 4, 2020
This week’s roundup features CHOP’s participation in a multi-institutional MIS-C research study — the first to provide long-term outcome data.

Dr. Oliver investigates the mechanisms governing T cell activation and protective immunity. Her goal is to define mechanisms that, when dysregulated, result in autoimmunity or allergic disorders like asthma.

E-mail:
oliverp1 [at] chop.edu

Dr. Romberg investigates the regulatory mechanisms enabling our immune systems to fight infections without injuring ourselves. He is particularly interested in the immune system of patients with primary immunodeficiency who are susceptible to both life-threatening infections and autoimmune diseases. Greater insights into these rare diseases may enable rationale development of targeted therapies for more common diseases with an immunologic basis.

E-mail:
rombergn [at] chop.edu