Common Variable Immunodeficiency | CHOP Research Institute

Healthy Children Needed for Single Study Visit on Immunometabolic Dysregulation

Healthy control children are needed to help participate in a study on Immunometabolic Dysregulation.

Romberg Laboratory

The Romberg Lab investigates the regulatory mechanisms enabling immune systems to fight infections without injuring ourselves. The lab is particularly interested in the immune system of primary immunodeficiency patients who are susceptible to both life-threatening infections and autoimmune diseases.

Sullivan Laboratory

The Sullivan Lab has a broad interest in immune dysfunction. This can underlie susceptibility to infections and autoimmunity and inflammation. The investigators in the lab use cutting-edge approaches to investigate cause in individual patients and to look at population-wide causes of disease.

Neil D. Romberg, MD

Dr. Romberg investigates the regulatory mechanisms enabling our immune systems to fight infections without injuring ourselves. He is particularly interested in the immune system of patients with primary immunodeficiency who are susceptible to both life-threatening infections and autoimmune diseases. Greater insights into these rare diseases may enable rationale development of targeted therapies for more common diseases with an immunologic basis.

E-mail:

rombergn [at] chop.edu

Kathleen E. Sullivan, MD, PhD

Dr. Sullivan's research focuses on new and rare immunodeficiencies. She has a long-standing interest in one of the most common of the primary immunodeficiencies – chromosome 22q11.2 deletion syndrome. She also investigates common variable immunodeficiency, as well as the genetics and epigenetics of systemic lupus erythematosus.

E-mail:

sullivank [at] chop.edu

VEPTR Inventor Dr. Robert Campbell Honored by Pennsylvania Bio

Published on

Mar 13, 2015

in Cornerstone Blog

Researchers from the Center for Applied Genomics at The Children’s Hospital of Philadelphia investigating a serious, rare disease called common variable immunodeficiency have discovered a gene linked to immune defense.