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In This Section
Yuanquan Song, PhD
Researcher
Dr. Song works to elucidate the cellular and molecular basis governing the formation, maintenance, and function of neural circuits under physiological and pathological conditions, using both Drosophila and mammalian models.
Bio
With a background in neural development, neural circuits and behavior, fly and mouse genetics, injury and tumor models, Dr. Song offers a unique skillset and perspective for addressing physiological questions in developmental/functional neurobiology, neurological diseases and tumorigenesis.
Education and Training
BS, Shanghai Jiao Tong University (Biotechnology), 2002
PhD, Perelman School of Medicine at the University of Pennsylvania (Neuroscience), 2009
Postdoctoral Fellowship, University of California, San Francisco (Physiology), 2016
Titles and Academic Titles
Researcher
Assistant Professor of Pathology and Laboratory Medicine
Professional Memberships
Society for Neuroscience, 2009-
Professional Awards
NIH/NINDS PA-11-197 NIH Pathway to Independence award (K99-R00)
IDDRC New Program Development Award/IDDRC at CHOP and Penn
CHOP Pilot grant
Roberts Functional Genomics Rapid Grant/CHOP
Roberts Collaborative Forefront Grant/CHOP
Craig H. Neilsen Foundation SCIRTS gran
Publication Highlights
Song Y, Li D, Farrelly O, Miles L, Li F, Kim SE, Lo TY, Wang F, Li T, Thompson-Peer KL, Gong J, Murthy SE, Coste B, Yakubovich N, Patapoutian A, Yang X, Rompolas P, Jan LY, Jan YN. The mechanosensitive ion channel Piezo inhibits axon regeneration. Neuron. 2019 Apr; 102(2):373-389.e6. PMID: 30819546
Li D, Li F, Guttipatti P, Song Y. A Drosophila in vivo injury model for studying neuroregeneration in the peripheral and central nervous system. J Vis Exp. 2018 May; (135). PMID: 29781994
Song Y, Sretavan D, Salegio EA, Berg J, Huang X, Cheng T, Meltzer S, Han C, Nguyen T, Bresnahan JC, Beattie MS, Jan LY, and Jan YN. Regulation of axon regeneration by the RNA repair/splicing pathway. Nat Neurosci. 2015 Jun; 18(6):817-25. PMID: 25961792
Han C, Song Y, Xiao H, Wang D, Franc N, Jan LY, Jan YN. Epidermal cells are the primary phagocytes in the fragmentation and clearance of degenerating dendrites in Drosophila. Neuron. 2014 Feb; 81(3):544-560. PMID: 24412417
Song Y, Ori-McKenney KM, Zheng Y, Han C, Jan LY, Jan YN. Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten and microRNA bantam. Genes Dev. 2012 Jul; 26(14):1612-25. PMID: 22759636