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Alexander G. Fiks, MD, MSCE
Alexander G. Fiks Headshot
Director, Clinical Futures

Dr. Fiks’ research is aimed at improving outcomes for ambulatory pediatric patients through primary care, practice-based scholarship with a focus on improving health and healthcare decision-making through health information technology.



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Dr. Fiks is a primary care pediatrician, a Professor of Pediatrics, and holds a Distinguished Endowed Chair in the Department of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania and Children’s Hospital of Philadelphia. Board certified in clinical informatics, Dr. Fiks’ research is aimed at improving outcomes for ambulatory pediatric patients through primary care practice-based research with a focus on improving health and healthcare decision-making through health information technology.

To achieve these goals, much of Dr. Fiks’ research has focused on fostering shared decision making between clinicians and families, often in the setting of behavioral health conditions. He is also especially interested in how electronic health record data may best be used to improve primary care, medication use and child health more broadly. With the American Academy of Pediatrics Pediatric Research in Office Settings Network, which he directs, Dr. Fiks has overseen the creation of the Collaborative Electronic Reporting for Comparative Effectiveness Research (CER2), an electronic health record database designed to support pharmacoepidemiologic and other comparative effectiveness studies that currently includes >1.2 million US children from across multiple health systems. 

Dr. Fiks is also the medical director for the Pediatric Research Consortium (PeRC), CHOP's practice-based research network, director of Clinical Futures, a CHOP Research Institute Center of Emphasis, a founding member of the hospital’s Department of Biomedical and Health Informatics, and faculty in PolicyLab. He also directs the Possibilities Project, a CHOP-based effort focused on primary care practice innovation and transformation.

Education and Training

AB, Harvard University (Biology), 1992

MD, Harvard University, 1997

MSCE, University of Pennsylvania (Epidemiology and Health Services Research), 2007

Titles and Academic Titles

Director, Clinical Futures

Medical Director, Pediatric Research Consortium

Director, The Possibilities Project

Distinguished Chair in the Department of Pediatrics

Founding Member, Department of Biomedical and Health Informatics

Attending Physician

Professor of Pediatrics

Professional Memberships

Academic Pediatric Association

American Academy of Pediatrics

American Medical Informatics Association

Society for Pediatric Research

Professional Awards

Young Investigator Award, Academic Pediatric Association, 2009

Outstanding Mentor Award, Academic Pediatric Association, 2012

Award for Patient Safety and Quality, Children's Hospital of Philadelphia, 2013

Young Physician-Scientist Award, American Society for Clinical Investigation, 2013

Publication Highlights

Szilagyi PG, Humiston SG, Stephens-Shields AJ, et al. Effect of Training Pediatric Clinicians in Human Papillomavirus Communication Strategies on Human Papillomavirus Vaccination Rates: A Cluster Randomized Clinical Trial. JAMA Pediatr. 2021 May; Published online May 24, 2021. doi:10.1001/jamapediatrics.2021.0766
Mayne, Stephanie L., et al. COVID-19 and Adolescent Depression and Suicide Risk Screening Outcomes. Pediatrics. 2021 Jan; Pediatrics, 2021, doi:10.1542/peds.2021-051507
Fiks AG, Friesen R, Biggs L. Consumerism, Innovation and the Future of Pediatric Primary Care. JAMA Pediatr. 2018 Sep; 172(9):797-798. doi: 10.1001/jamapediatrics.2018.1501
Fiks AG, Scheindlin B, Shone LP. 30th Anniversary of Pediatric Research in Office Settings (PROS): An Invitation to Become Engaged.. Pediatrics. 2016 Sep; 138(3). pii: e20161126. doi: 10.1542/peds.2016-1126. Epub 2016 Aug 2
Fiks AG, Mayne S, Karavite D, Suh A, O'Hara R, Localio R, Ross M, Grundmeier RW. Parent-Reported Outcomes of a Shared Decision Making Portal in Asthma: A Practice-based RCT. Pediatrics. 2015 Apr; 135(4):e965-73. doi: 10.1542/peds.2014-3167. Epub 2015 Mar 9

Links of Interest