Immune Dysregulation Program News & Announcements

Research news highlights the value of serum cytokine panels in disease management and preclinical work to develop a mRNA vaccine to treat and prevent C. diff.

CHOP researchers study the effect of high-stress neighborhoods on mental health and the implications of improved rare disease diagnosis.

USIDNET will enhance its resources to improve the state of genetic diagnostics for patients with primary immunodeficiency diseases.

Learn about novel findings and notable achievements from our Children’s Hospital of Philadelphia researchers.

Researchers used deep immune profiling to better understand immune activation in children with multisystem inflammatory syndrome.

Our most engaging stories of 2020 highlight moments of positivity, hope, and inspiration in a year of challenge and change.

SARS-CoV-2 Infections, even those with minimal or no symptoms, are linked to blood vessel damage in children.

CHOP researchers found an elevated biomarker in all children who tested positive SARS-CoV-2, regardless of COVID-19 symptoms.

Researchers published the first report of pediatric patients treated with convalescent plasma for SARS-CoV-2 associated acute respiratory distress syndrome.

The first study to report on convalescent plasma in life-threatening cases of the virus makes the case for a larger, randomized trial.

Researchers at CHOP are studying the features and causes of multisystem inflammatory syndrome in children.

CHOP data differentiates MIS-C from severe COVID-19, and suggests that MIS-C is a post-infectious syndrome related to the infection.

David Teachey, MD, and colleagues are exploring convalescent plasma as a treatment for COVID-19, the disease caused by SARS-CoV-2.

Teams at CHOP are using a collaborative approach to identify and test potential treatments for COVID-19.

A multidisciplinary team of physician-researchers at CHOP are studying the role of cytokine storms in COVID-19.