Ulcerative Colitis | CHOP Research Institute

Mini-Intestines: CHOP Researchers Use Lab-Grown Organoids to Study, Treat IBD

Published on

Aug 14, 2023

CHOP Researchers Use Mini Intestines to Study, Treat IBD

By studying lab-grown organoids derived from patients’ stem cells, the Hamilton Lab seeks to better understand and treat IBD.

Peter Mattei, MD

Dr. Mattei is an attending physician in the Division of General, Thoracic and Fetal Surgery and specializes in pediatric surgical oncology, inflammatory bowel disease, and minimally invasive and robotic surgery. His research interests are in oncology and IBD.

E-mail:

mattei [at] chop.edu

Tofa For UC

The purpose of this research study is to help us understand how well tofacitinib works as a treatment for ulcerative colitis or indeterminate colitis in pediatric patients.

UC Diet

Announcing a new diet trial for patients with an established diagnosis of UC.

Christopher J. Cardinale, MD, PhD

Dr. Cardinale's research is focused on understanding the mechanisms of gene expression and gene regulation in autoimmune diseases, including inflammatory bowel disease, type 1 diabetes, and systemic sclerosis. He uses data from large-scale genomic studies to identify disease-causing genetic variants and functionally explore the target genes of those variants.

E-mail:

cardinalec [at] chop.edu

Pediheart Podcast, EPA Asthma Award, Walk for Hope, Antibiotics and Kidney Stones, Gilyena Approval, Autism Challenge

Published on

May 18, 2018

in Cornerstone Blog

This week in the news, research from the Cardiac Center and the Division of Urology make headlines for children's health.

On Your Skin, In Your Gut, and All Around: A Microbiome Q&A

Published on

Jul 5, 2016

in Cornerstone Blog

Microbes are on us and in us, and researchers are increasingly becoming aware that they are a vital part of us. Across The Children's Hospital of Philadelphia and University of Pennsylvania a variety of research efforts are underway to understand these populations of bacteria, viruses, and other tiny life forms, known as the microbiome, and their impact on health.