Host-pathogen Interactions | CHOP Research Institute
 

Host-pathogen Interactions

The Center for Microbial Medicine at Children’s Hospital of Philadelphia leverages the microbiome to improve the health of children and bring personalized microbiome-based medicine from bench to bedside to every child who receives care at CHOP.

The Zackular Lab seeks to understand how interactions between the host, gut microbiota, and pathogenic microbes impact human health and disease.

Published on
Aug 31, 2022
Our featured Faculty Spotlight for August, Joseph Zackular, PhD, studies the interaction between Clostridioides difficile and microbes.

Dr. Zackular's research is focused on understanding how interactions between the host, gut microbiota, and pathogenic microbes impact human health and disease. His recent efforts center on understanding how the important nosocomial pathogen, Clostridium difficile, interacts with resident gut microbiota during infection and how interspecies cross-talk impacts growth, behavior, and virulence of this pathogen.

E-mail:
zackularj [at] chop.edu