Eosinophilic Esophagitis | CHOP Research Institute

Eosinophilic Esophagitis

Published on
Jan 6, 2023
See highlights of work by Children’s Hospital of Philadelphia researchers that is leading to novel findings.

Dr. Ruchelli is an attending pathologist with the Congenital Hyperinsulinism Center and the Division of Anatomic Pathology at CHOP, and an associate professor of pathology and laboratory medicine at the University of Penn. His research focuses on congenital hyperinsulinism and eosinophilic esophagitis.

ruchelli [at] chop.edu
Published on
May 25, 2022
Elizabeth Bhoj, MD, PhD, and David Hill, MD, PhD, are recipients of a 2021 Individual Biomedical Research Award from The Hartwell Foundation.

Dr. Merves has a background in basic and clinical translational research in eosinophilic esophagitis. Her more recent focus is clinical research in the pediatric short-bowel population. Dr. Merves is currently evaluating blenderized feeding in the pediatric short bowel population.

gilbergj [at] chop.edu

The main objective of this study is to see if repeat subcutaneous doses of dupilumab, the study medicine, helps to reduce eosinophilic inflammation in the stomach of participants with eosinophilic gastritis/ eosinophilic gastroenteritis compared to a placebo.

Published on
Nov 26, 2021
Learn about novel findings and new funding from our Children’s Hospital of Philadelphia researchers.

The Ruffner Lab's long-term goal is to understand how the interactions between the immune system and mucosal barrier are altered in patients with food allergies.

Eosinophilic esophagitis involves chronic allergic inflammation with tissue damage leading to fibrosis. The goal of the Muir Lab is to elucidate the mechanisms of esophageal fibrosis and to improve its therapeutic and diagnostic approaches.

Scientists in the Hill Lab seek to understand how the immune system contributes to the two most common chronic diseases of childhood: allergy and obesity. The lab uses clinical and epidemiological information to guide basic and translational research aimed at understanding the genetic, epigenetic, and immunologic basis of these diseases.

Conducting laboratory, translational, and clinical research to revolutionize medications and therapies aimed at eradicating childhood food allergies.