Eosinophilic Esophagitis | CHOP Research Institute
 

Eosinophilic Esophagitis

In The News: MIS-C, Antibody Treatment for Eosinophilic Esophagitis, ASH 2022

Published on
Jan 6, 2023
in Cornerstone Blog
Our Scientists’ Research Highlighted In the News
See highlights of work by Children’s Hospital of Philadelphia researchers that is leading to novel findings.
Eduardo Ruchelli, MD
Eduardo Ruchelli

Dr. Ruchelli is an attending pathologist with the Congenital Hyperinsulinism Center and the Division of Anatomic Pathology at CHOP, and an associate professor of pathology and laboratory medicine at the University of Penn. His research focuses on congenital hyperinsulinism and eosinophilic esophagitis.

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E-mail:
ruchelli [at] chop.edu

Hartwell Awards Fund ‘Innovative, Early-Stage’ Research for Two CHOP Investigators

Published on
May 25, 2022
in Cornerstone Blog
Two CHOP Investigators Receive Hartwell Awards
Elizabeth Bhoj, MD, PhD, and David Hill, MD, PhD, are recipients of a 2021 Individual Biomedical Research Award from The Hartwell Foundation.
Jamie Merves, MD
Jamie Merves

Dr. Merves has a background in basic and clinical translational research in eosinophilic esophagitis. Her more recent focus is clinical research in the pediatric short-bowel population. Dr. Merves is currently evaluating blenderized feeding in the pediatric short bowel population.

E-mail:
gilbergj [at] chop.edu

DEGAS

The main objective of this study is to see if repeat subcutaneous doses of dupilumab, the study medicine, helps to reduce eosinophilic inflammation in the stomach of participants with eosinophilic gastritis/ eosinophilic gastroenteritis compared to a placebo.

In the News: MRSA, EoE Clinical Trial, Rare Disease, Exploring the Hypothalamus

Published on
Nov 26, 2021
in Cornerstone Blog
MRSA, EoE Clinical Trial, Rare Disease, Exploring the Hypothalamus
Learn about novel findings and new funding from our Children’s Hospital of Philadelphia researchers.

Ruffner Laboratory

Ruffner Lab

The Ruffner Lab's long-term goal is to understand how the interactions between the immune system and mucosal barrier are altered in patients with food allergies.

Muir Laboratory

Muir Lab

Eosinophilic esophagitis involves chronic allergic inflammation with tissue damage leading to fibrosis. The goal of the Muir Lab is to elucidate the mechanisms of esophageal fibrosis and to improve its therapeutic and diagnostic approaches.

Hill Laboratory

Hill Lab

Scientists in the Hill Lab seek to understand how the immune system contributes to the two most common chronic diseases of childhood: allergy and obesity. The lab uses clinical and epidemiological information to guide basic and translational research aimed at understanding the genetic, epigenetic, and immunologic basis of these diseases.

Food Allergy Center

Food Allergy Center

Conducting laboratory, translational, and clinical research to revolutionize medications and therapies aimed at eradicating childhood food allergies.