Neurodegeneration | CHOP Research Institute
 

Neurodegeneration

Neuroregenerative Mechanisms May Protect Against Neurodegenerative Diseases

Published on
Jan 4, 2023
in Cornerstone Blog
Yuanquan Song, PhD
Researchers are studying whether the mechanisms behind neuroregeneration could provide insight to protective mechanisms against neurodegeneration.

‘Progress to Benefit Patients:’ Faculty Spotlight With Elizabeth Bhoj, MD, PhD

Published on
Feb 28, 2022
in Cornerstone Blog
Faculty Spotlight With Elizabeth Bhoj, MD, PhD
From bench to bedside, Dr. Bhoj studies rare genetic disorders, particularly neurologic syndromes.

Faculty Spotlight: Naiara Akizu Lopez, PhD, Merges Research Passions

Published on
Aug 31, 2021
in Cornerstone Blog
Naiara Akizu Lopez, PhD, Merges Research Passions
Our August Faculty Spotlight scientist, Naiara Akizu Lopez, PhD, studies the genetic and epigenetic mechanisms of neurologic disorders in children.

Lynch Laboratory

Lynch Lab

The Lynch Lab conducts clinical, translational, and basic science research on the rare disease Friedreich ataxia

Akizu Laboratory

Akizu Lab

Research in the Akizu Lab aims to better understand human brain complexity in health and disease, with the ultimate goal of uncovering therapeutic targets for pediatric neurodegenerative disorders.

Cell Biology Research Affinity Group

Cell Biology Research Affinity Group

Investigating the cell biological basis of disease.

Clinical Geneticists Seek Novel Pathways of Pediatric Neurodegenerative Disease

Published on
Aug 19, 2020
in Cornerstone Blog
Neurodegenerative Disease
Researchers will study the mechanisms behind novel pediatric neurodegenerative disorders and assess their role in adult-onset conditions.

Bhoj Laboratory

Bhoj Lab

The Bhoj Lab is a genetics lab that discovers new human disease genes, their mechanisms, and potential targeted therapies. In addition to ongoing gene discovery efforts, the lab focuses on three novel genes that lead to pediatric neurologic dysfunction: TBCK, H3F3A/B, and MAP4K4.

Elizabeth J.K. Bhoj, MD PhD
Elizabeth J.K. Bhoj

Dr. Bhoj's genetics research aims to discover new human disease genes, their mechanisms, and potential targeted therapies. In addition to ongoing gene discovery efforts, Dr. Bhoj focuses on three novel genes that lead to pediatric neurologic dysfunction: TBC1 domain-containing kinase, Histone 3.3 (H3F3A and H3F3B), and MAP4K4.

E-mail:
bhoje [at] chop.edu
David R. Lynch, MD, PhD
David R. Lynch

Dr. Lynch maintains a dynamic program that involves clinical, translational, and basic science research efforts focused on the rare disease Friedreich ataxia.

E-mail:
lynch [at] chop.edu