Neurodegeneration | CHOP Research Institute
 

Neurodegeneration

Published on
Oct 26, 2023
Xilma Ortiz-Gonzalez, MD, PhD, guest speaker at the 2023 TBCK Conference, shares new research for a rare, progressive, neurodegenerative disease.
Published on
Jan 4, 2023
Researchers are studying whether the mechanisms behind neuroregeneration could provide insight to protective mechanisms against neurodegeneration.
Published on
Feb 28, 2022
From bench to bedside, Dr. Bhoj studies rare genetic disorders, particularly neurologic syndromes.
Published on
Aug 31, 2021
Our August Faculty Spotlight scientist, Naiara Akizu Lopez, PhD, studies the genetic and epigenetic mechanisms of neurologic disorders in children.

The Lynch Lab conducts clinical, translational, and basic science research on the rare disease Friedreich ataxia

Research in the Akizu Lab aims to better understand human brain complexity in health and disease, with the ultimate goal of uncovering therapeutic targets for pediatric neurodegenerative disorders.

Investigating the cell biological basis of disease.

Published on
Aug 19, 2020
Researchers will study the mechanisms behind novel pediatric neurodegenerative disorders and assess their role in adult-onset conditions.

The Bhoj Lab discovers new human disease genes, their mechanisms, and potential targeted therapies. A bedside-to-bench-to-bedside translational lab that brings discoveries back to patients, we are focused on three novel genes that lead to pediatric neurologic dysfunction: TBCK, H3F3A/B, and MAP4K4.

Dr. Bhoj's genetics research aims to discover new human disease genes, their mechanisms, and potential targeted therapies. In addition to ongoing gene discovery efforts, Dr. Bhoj focuses on three novel genes that lead to pediatric neurologic dysfunction: TBC1 domain-containing kinase, Histone 3.3 (H3F3A and H3F3B), and MAP4K4.

E-mail:
bhoje [at] chop.edu