Mitochondria | CHOP Research Institute

In the News: FDA Approval, Mitochondrial Dysfunction, Pediatric Headaches

Published on

Aug 18, 2023

In the News: FDA Approval, Mitochondrial Dysfunction

The FDA approved an oral drug, based on foundational research conducted at CHOP, to treat a rare, severe bone disease. More In The News.

Tableside Chat About Mitochondria Leads to Gates Foundation Grant for COVID-19 Research

Published on

Mar 2, 2023

in Cornerstone Blog

Tableside Chat Leads to Gates Foundation Grant for CHOP

With a grant from the Gates Foundation, CHOP researchers are working to determine the importance of mitochondria DNA variation in COVID-19 severity.

Understanding Mitochondrial Adaptation: Q&A With Diversity Fellow Arnold Olali, PhD

Published on

Dec 27, 2022

in Cornerstone Blog

Q&A With Diversity Fellow Arnold Olali, PhD

Featured Diversity Fellow Arnold Olali, PhD, is focused on understanding how mitochondria affect overall health.

In The News: Environmental Hazards, Physician of the Year, Lifetime Achievement Award, Special Podcast Series

Published on

Apr 1, 2022

in Cornerstone Blog

Learn about earn about a regional research collaboration, prestigious awards, and listen to a special podcast series.

MC² Program Energizes Research Between Mitochondrial Disease and Pediatric Cancer

Published on

Sep 22, 2021

in Cornerstone Blog

MC² Program Energizes Research Between Mitochondrial Disease and Pediatric Cancer

Marni Falk, MD, and Adam Resnick, PhD, to lead the Mitochondria and Cancer Connections (MC²) Research Program, a new CHOP research initiative.

Wallace Laboratory

The Wallace Laboratory investigates the role of mitochondria in human evolution, health, and disease.

The McCormack Lab studies the intersection of neuroendocrinology and metabolism, with two areas of focus. First, the lab studies genetic disorders with increased risk for diabetes mellitus, including mitochondrial diseases. Second, investigators in the lab focus on brain tumor-related hypothalamic obesity syndrome.

Ischiropoulos Laboratory

The research objectives of the Ischiropoulos Lab are to elucidate the nitric oxide signaling pathways at the proteome level in the cardiovascular and neuronal systems; define the molecular mechanisms by which nitric oxide signaling regulates metabolic pathways during development and aging; and develop and test novel therapeutics for long-chain f

Mitochondrial Medicine

Converging individualized basic, translational, and clinical research programs dedicated to improving the health of patients of all ages living with mitochondrial disease.

Kilbaugh Laboratory

The Kilbaugh Lab focuses on advanced therapies for treating cardiac arrest, traumatic brain injuries, cardiopulmonary bypass, extracorporeal life support, defense against chemical toxins, and therapeutics for mitochondrial disorders that reduce neurological damage.