Mitochondria

The Wallace Laboratory investigates the role of mitochondria in human evolution, health, and disease.

The Robinson Laboratory has had a longstanding interest in the function and regulation of brain glutamate transport under physiologic and pathologic conditions.

The McCormack Lab studies the intersection of neuroendocrinology and metabolism, with two areas of focus. First, the lab studies genetic disorders with increased risk for diabetes mellitus, including mitochondrial diseases. Second, investigators in the lab focus on brain tumor-related hypothalamic obesity syndrome.

The research objectives of the Ischiropoulos Lab are to elucidate the nitric oxide signaling pathways at the proteome level in the cardiovascular and neuronal systems; define the molecular mechanisms by which nitric oxide signaling regulates metabolic pathways during development and aging; and develop and test novel therapeutics for long-chain f

Converging individualized basic, translational, and clinical research programs dedicated to improving the health of patients of all ages living with mitochondrial disease.

The Kilbaugh Lab focuses on advanced therapies for treating cardiac arrest, traumatic brain injuries, cardiopulmonary bypass, extracorporeal life support, defense against chemical toxins, and therapeutics for mitochondrial disorders that reduce neurological damage.