Brain Tumors | CHOP Research Institute
 

Brain Tumors

Published on
Sep 3, 2025
Researchers identified a potential therapeutic vulnerability in pediatric high-grade gliomas.
Published on
Apr 9, 2025
Jessica Foster, MD, this month’s Faculty Spotlight, is working hard to bring immunotherapy treatments for brain and spinal cord tumors from bench to bedside.

The Bhatia Laboratory develops and evaluates advanced imaging techniques to further understand the imaging biomarkers of brain tumors in children that will help in diagnosis, prognosis, and accurate monitoring of treatments.

Published on
Sep 19, 2022
CHOP physician-scientists discuss their CAR T-cell therapy research for childhood cancers in Where Discovery Leads.

The Philadelphia Coalition for a Cure (PC4C) study is interested in collecting blood and saliva samples from you, as well as leftover tissue and cerebrospinal fluid from surgeries at CHOP.

Evaluate the side effects and benefits of ALRN-6924 in patients with relapsed or treatment refractory solid tumor or brain tumor, and to determine the best dose of ALRN-6924 for children and adolescents.

The overall goals of this study are to evaluate the side effects and benefits of CUDC-907 in patients with relapsed or treatment refractory solid tumor, brain tumor, or lymphoma, and to determine the best dose of CUDC-907 for children and adolescents.

Work in the Resnick and Storm Lab focuses on the cell signaling mechanisms of oncogenesis and tumor progression in brain tumors. The lab studies signaling cascades and alterations to elucidate the molecular and genetic underpinnings in order to develop targeted therapies.

The Maris Lab leverages insights into the basic mechanisms underlying childhood cancer initiation and progression into novel, curative treatments for neuroblastoma and other pediatric malignancies.

The Children Brain Tumor Tissue Consortium (CBTTC) is a collaborative multi-institutional cooperative research program dedicated to the study of childhood brain tumors.