Solid Tumors | CHOP Research Institute
 

Solid Tumors

Published on
Oct 1, 2025
Kyrie was diagnosed with a rare cancer at 6 years old. His participation in a clinical trial paved the way for a new frontline therapy.
Published on
Apr 3, 2025
PEEL-224, a therapy to treat high-risk tumors, enters a pediatric clinical trial after a decade of groundbreaking research.

This study enrolls patients with refractory, progressive, or relapsed solid tumors.

This study involves taking a study drug called INBRX-109.

This study enrolls patients with newly diagnosed differentiated thyroid cancer (papillary thyroid cancer or follicular thyroid cancer) that has spread to the lungs and has a genetic mutation called and RET fusion.

This study involves an investigational cellular therapy called Afamitresgene Autoleucel.

The Grupp Lab develops new targeted cancer treatments and cell-based immunotherapies for leukemia and solid tumors, and aims to create advanced, less toxic treatments for children with high-risk cancers.

This study involves taking a study drug called tegavivint. The study will be testing different doses of the study drug to find the safest dose.

This study enrolls patients that have been diagnosed with SMARCB1 or SMARCB4 deficient cancer that has either come back (“relapsed”) or does not respond to therapy (“is refractory”) or have been newly diagnosed with a SMARCB1 or SMARCB4 deficient cancer that has no known standard treatment.

This study involves a taking a study drug called vactosertib by mouth.