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Shih-Shan Lang Chen, MD
Attending Neurosurgeon
Dr. Chen's research focuses on traumatic brain injury (TBI), multimodal neuromonitoring, and neurovascular disorders. She is interested in non-invasive forms of neuromonitoring thus leading to research efforts identifying reliable non-invasive methods for detecting intracranial hypertension in multiple disease processes including TBI and craniosynostosis.
Bio
Dr. Chen is an attending neurosurgeon at CHOP. Her research endeavors are centered in traumatic brain injury (TBI), multimodal neuromonitoring, and neurovascular disorders. She generates data in pediatric traumatic TBI outcomes and treatments based upon clinical data and CHOP’s TBI database and biobanking.
Dr. Chen is interested in non-invasive forms of neuromonitoring thus leading to research efforts identifying reliable non-invasive methods for detecting intracranial hypertension in multiple disease processes including TBI and craniosynostosis.
As director of Vascular Neurosurgery, where she heads the neurovascular biobanking, she aims to identifying genetic and protein markers of vascular disorders.
Education and Training
BS, University Of Florida (Neurobiological Sciences), 2002
MD, University Of Florida College Of Medicine, 2007
Internship, Hospital of the University of Pennsylvania (General Surgery)
Residency, Hospital of the University of Pennsylvania (Neurosurgery (Chief Resident)
Fellowship, Children's Hospital of Philadelphia (Pediatric Neurosurgery)
Titles and Academic Titles
Attending Neurosurgeon
Associate Director, Trauma Center
Director of Vascular Neurosurgery
Assistant Professor of Neurosurgery
Professional Memberships
American Society of Pediatric Neurosurgeons, 2020-
International Pediatric Craniofacial Collaborative Group
Consensus statement expert panel, 2020-
American Board of Neurological Surgery, 2019-
American Board of Pediatric Neurological Surgery, 2019-
American Academy of Neurological Surgeons, 2008-
Congress of Neurological Surgeons, 2008-
Professional Awards
Top Abstract, Near Infrared Spectroscopy Monitoring in Pediatric Abusive Head Trauma, American Society of Pediatric Neurosurgeons 46th Annual Meeting, 2023
AANS/CNS Peds section meeting Evidence Based Medicine Best Paper, "Invasive Brain Tissue Oxygen and Intracranial Pressure (ICP) Monitoring versus ICP-only Monitoring in Pediatric Severe Traumatic Brain Injury," 2022
Chief Resident in Neurological Surgery, University of Pennsylvania, 2013-2014
Fellowship grant CP Angle Endoscopic, Microvascular Decompression, Karl Storz, 2013
Enfolded Fellowship in endoscopic skull base neurosurgery, University of Pennsylvania, 2012
Society for Neuro-Oncology Award for Excellence in Pediatric Translational Research, 2012
Congress of Neurological Surgeons Preuss Award for Basic Science Tumor Research, 2012
Pan Philadelphia Basic Science Research Award, 2011
Medical Student Surgery Ambrose Pace Scholarship, 2007
Junior Alpha Omega Alpha, 2006
College of Medicine Alumni Scholarship for Academic Excellence, 2006
Academic Perfection Award, College of Medicine, 2004-2006
Publication Highlights
PubMed:
Tucker AM, Madsen PJ, Coyle AM, King H, Zahner C, Lang SS, Taylor JA, Heuer GG. Preprocedural Electrophysiological Monitoring in Craniofacial Surgery for a Patient with Chiari Malformation. Cleft Palate Craniofac J. 2022 Nov; 10556656221135284. PMID: 36357356
Blum JD, Beiriger J, Kalmar C, Avery RA, Lang SS, Villavisanis DF, Cheung L, Cho DY, Tao W, Whitaker R, Bartlett SP, Taylor JA, Goldstein JA, Swanson JW. Relating Metopic Craniosynostosis Severity to Intracranial Pressure. J Craniofac Surg. 2022 Nov; 33(8): 2372-2378. PMID: 35864584
Zapatero ZD, Kosyk MS, Kalmar CL, Cheung L, Carlson AR, Heuer GG, Bartlett SP, Taylor JA, Lang SS, Swanson JW. How Low Should We Go? Safety and Craniometric Impact of the Low Occipital Osteotomy in Posterior Vault Remodeling. Plast Reconstr Surg. 2022 Nov; 150(5): 1037e-1048e. PMID: 3599
Kundishora AJ, Peters ST, Pinard A, Duran D, Panchagnula S, Barak T, Miyagishima DF, Dong W, Smith H, Ocken J, Dunbar A, Nelson-Williams C, Haider S, Walker RL, Li B, Zhao H, Thumkeo D, Marlier A, Duy PQ, Diab NS, Reeves BC, Robert SM, Sujijantarat N, Stratman AN, Chen YH, Zhao S, Roszko I, Lu Q, Zhang B, Mane S, Castaldi C, López-Giráldez F, Knight JR, Bamshad MJ, Nickerson DA, Geschwind DH, Chen SL, Storm PB, Diluna ML, Matouk CC, Orbach DB, Alper SL, Smith ER, Lifton RP, Gunel M, Milewicz DM, Jin SC, Kahle KT. DIAPH1 Variants in Non-East Asian Patients With Sporadic Moyamoya Disease. JAMA Neurol. 2021 Aug; 78(8): 993-1003. PMID: 34125151