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John M. Maris, MD
John M. Maris
Giulio D’Angio Endowed Professor of Pediatrics

Dr. Maris is a physician and scientist focused on discovering the basic mechanisms of childhood cancers, what makes subsets of cancers highly aggressive and resistant to standard therapies, and using this knowledge to create new precision therapeutics.

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Bio

Dr. Maris is a physician and scientist who has focused on the childhood cancer neuroblastoma for more than three decades. His dual goals are to improve patient outcomes and use the disease as a model to advance understanding of cancer in general.

The Maris Laboratory has discovered the vast majority of the currently known neuroblastoma susceptibility genes through both family-based and genome-wide association study approaches.

Dr. Maris is an internationally recognized practicing pediatric oncologist who cares for children with refractory neuroblastoma, typically in the context of early phase clinical trials. He aims to make paradigm-shifting laboratory advances that are immediately applicable to improving outcomes for patients.
He supports diverse and multidisciplinary research teams within his lab and as a leader of several multi-institutional projects, and has mentored more than 100 trainees in various disciplines over the past 25 years. Dr. Maris also maintains a clinical practice exclusive to children with cancer for whom currently available therapies were unsuccessful. Through highly integrated basic and clinical research programs, he continuously seeks to improve patient outcomes.

Education and Training

BS, Wheeling College (Biology), 1983

MD, University of Pennsylvania School of Medicine (Medicine), 1989

Resident, Children's Hospital of Philadelphia/University of Pennsylvania (Pediatrics), 1992

Fellow, Children's Hospital of Philadelphia (Pediatric Hematology/Oncology), 1995

Postdoctoral Fellow, Children's Hospital of Philadelphia (Cancer Genetics), 1996

Titles and Academic Titles

Attending Physician

Giulio D'Angio Chair in Neuroblastoma Research

Professor of Pediatrics

Professional Memberships

Chair, COG Neuroblastoma Disease Committee, 2006-2010

Member, COG ANBL0621 Study Committee, 2006-2010

Member, NANT 2007-01 Study Committee, 2007-2011

Vice-Chair, COG ADVL0812 Study Committee, 2008-2012

Member, COG ANBL0821 Study Committee, 2008-2012

Member, COG ANBL0823 Study Committee, 2008-2013

Member, AACR Pediatric Oncology Task Force, 2009-present

Member, ASPHO Professional Development Committee, 2010-present

Member, AACR Special Conferences Committee, 2010-2013

Member, AACR Stand up to Cancer Review Committee, 2010-present

Member, COG Scientific Council and Associate Chair, 2011-present

Member, ASCO Leadership Development Program Working Group, 2011-2015

Member, AACR Cancer Progress Report 2012 Writing Committee

Member, AACR Vision 2020 Strategic Planning Committee, 2015-2018

Member, Pediatric Cancer Working Group, NCI Cancer Moonshot Blue Ribbon Panel, 2016-2018

Chair, NCI Cancer Moonshot Pediatric Immunotherapy Discovery and Development Steering Committee, 2019-present

Member, NCI Board of Scientific Advisors ad hoc Working Group: Childhood Cancer Data Initiative

Member, Foundation of the NIH Working Group: Pediatric Preclinical Testing Public-Private Partnership

Co-leader, Childhood Cancer Data Initiative Open Targets Project

Co-Chair, Pediatric Immunotherapy Network Steering Committee, 2023-

Professional Awards

Alpha Omega Alpha, 1988

Pincus Award: Outstanding Clinician of Graduating Medical School Class, 1989

American Society of Pediatric Hematology/Oncology Young Investigator Award, 1993

Elected to the Society for Pediatric Research, 2004

Oski Award Recipient, American Society of Pediatric Hematology/Oncology, 2007

Elected to the American Society of Clinical Investigation, 2007

Leonard Berwick Memorial Teaching Award, University of Pennsylvania School of Medicine, for integrating the basic and clinical sciences, 2009

Eagles Fly for Leukemia Lifetime Achievement Award, 2009

William Osler Patient Oriented Research Award, University of Pennsylvania School of Medicine, 2010

Elected to the John Morgan Society, University of Pennsylvania, 2012

Award of Excellence, Arms Wide Open Foundation, 2013

St. Ignatius Loyola Distinguished Alumni Award, Wheeling University, 2013

National Cancer Institute Outstanding Investigator Award, 2017

National Cancer Institute Eminent Lecture, 2018

American Association for Cancer Research Team Science Award (Pediatric Cancer Dream Team Leader), 2021

Party with a Purpose Scientific Achievement Award, Friend of the AACR Foundation, 2023

Elected to the Association of American Physicians, 2024

Elected as a Fellow to the American Association for Cancer Research Academy, 2024

Children’s Hospital of Philadelphia and Alex’s Lemonade Stand Pitcher of Hope Award, 2024

Philadelphia Ronald McDonald House 50th Anniversary Dr. Audrey Evans Award for Medical Excellence (with Dr. Yael Mossé), 2024

Publication Highlights

Links of Interest