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In This Section
Dr. Maris is a physician and scientist focused on discovering the basic mechanisms of childhood cancers, what makes subsets of cancers highly aggressive and resistant to standard therapies, and using this knowledge to create new precision therapeutics.
Bio
Dr. Maris is a physician and scientist who has focused on the childhood cancer neuroblastoma for more than three decades. His dual goals are to improve patient outcomes and use the disease as a model to advance understanding of cancer in general.
The Maris Laboratory has discovered the vast majority of the currently known neuroblastoma susceptibility genes through both family-based and genome-wide association study approaches.
Dr. Maris is an internationally recognized practicing pediatric oncologist who cares for children with refractory neuroblastoma, typically in the context of early phase clinical trials. He aims to make paradigm-shifting laboratory advances that are immediately applicable to improving outcomes for patients.
He supports diverse and multidisciplinary research teams within his lab and as a leader of several multi-institutional projects, and has mentored more than 100 trainees in various disciplines over the past 25 years. Dr. Maris also maintains a clinical practice exclusive to children with cancer for whom currently available therapies were unsuccessful. Through highly integrated basic and clinical research programs, he continuously seeks to improve patient outcomes.
Education and Training
BS, Wheeling College (Biology), 1983
MD, University of Pennsylvania School of Medicine (Medicine), 1989
Resident, Children's Hospital of Philadelphia/University of Pennsylvania (Pediatrics), 1992
Fellow, Children's Hospital of Philadelphia (Pediatric Hematology/Oncology), 1995
Postdoctoral Fellow, Children's Hospital of Philadelphia (Cancer Genetics), 1996
Titles and Academic Titles
Attending Physician
Giulio D'Angio Chair in Neuroblastoma Research
Professor of Pediatrics
Professional Memberships
Chair, COG Neuroblastoma Disease Committee, 2006-2010
Member, COG ANBL0621 Study Committee, 2006-2010
Member, NANT 2007-01 Study Committee, 2007-2011
Vice-Chair, COG ADVL0812 Study Committee, 2008-2012
Member, COG ANBL0821 Study Committee, 2008-2012
Member, COG ANBL0823 Study Committee, 2008-2013
Member, AACR Pediatric Oncology Task Force, 2009-present
Member, ASPHO Professional Development Committee, 2010-present
Member, AACR Special Conferences Committee, 2010-2013
Member, AACR Stand up to Cancer Review Committee, 2010-present
Member, COG Scientific Council and Associate Chair, 2011-present
Member, ASCO Leadership Development Program Working Group, 2011-2015
Member, AACR Cancer Progress Report 2012 Writing Committee
Member, AACR Vision 2020 Strategic Planning Committee, 2015-2018
Member, Pediatric Cancer Working Group, NCI Cancer Moonshot Blue Ribbon Panel, 2016-2018
Chair, NCI Cancer Moonshot Pediatric Immunotherapy Discovery and Development Steering Committee, 2019-present
Member, NCI Board of Scientific Advisors ad hoc Working Group: Childhood Cancer Data Initiative
Member, Foundation of the NIH Working Group: Pediatric Preclinical Testing Public-Private Partnership
Co-leader, Childhood Cancer Data Initiative Open Targets Project
Co-Chair, Pediatric Immunotherapy Network Steering Committee, 2023-
Professional Awards
Alpha Omega Alpha, 1988
Pincus Award: Outstanding Clinician of Graduating Medical School Class, 1989
American Society of Pediatric Hematology/Oncology Young Investigator Award, 1993
Elected to the Society for Pediatric Research, 2004
Oski Award Recipient, American Society of Pediatric Hematology/Oncology, 2007
Elected to the American Society of Clinical Investigation, 2007
Leonard Berwick Memorial Teaching Award, University of Pennsylvania School of Medicine, for integrating the basic and clinical sciences, 2009
Eagles Fly for Leukemia Lifetime Achievement Award, 2009
William Osler Patient Oriented Research Award, University of Pennsylvania School of Medicine, 2010
Elected to the John Morgan Society, University of Pennsylvania, 2012
Award of Excellence, Arms Wide Open Foundation, 2013
St. Ignatius Loyola Distinguished Alumni Award, Wheeling University, 2013
National Cancer Institute Outstanding Investigator Award, 2017
National Cancer Institute Eminent Lecture, 2018
American Association for Cancer Research Team Science Award (Pediatric Cancer Dream Team Leader), 2021
Party with a Purpose Scientific Achievement Award, Friend of the AACR Foundation, 2023
Elected to the Association of American Physicians, 2024
Elected as a Fellow to the American Association for Cancer Research Academy, 2024
Children’s Hospital of Philadelphia and Alex’s Lemonade Stand Pitcher of Hope Award, 2024
Philadelphia Ronald McDonald House 50th Anniversary Dr. Audrey Evans Award for Medical Excellence (with Dr. Yael Mossé), 2024
Publication Highlights
Links of Interest
CHOP's John M. Maris MD, and Penn Medicine's E. John Wherry named 2024 Fellows of the AACR Academy
CHOP Cancer Researchers Win 2021 AACR Team Science Award
Dr. John Maris: Teaming Up to End Childhood Cancer
Dr. John Maris Presented with the Alex’s Lemonade Stand 2024 Pitcher of Hope Award
Alex’s Lemonade Stand Powers 20 Years of Pediatric Cancer Research at CHOP
Cell and gene therapies against pediatric cancers.
John Maris, MD, Receives Outstanding Investigator Award
https://scholar.google.com/citations?user=JnM1FjgAAAAJ&hl=en8