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coulterd [at]
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3615 Civic Center Blvd
Philadelphia, PA 19104
United States

Douglas A. Coulter, PhD
Douglas A. Coulter

Dr. Coulter conducts physiological studies examining mechanisms of epilepsy. His research centers on injury-induced epilepsies as well as genetically-induced epilepsy, autism, and developmental intellectual disabilities.



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Education and Training

BS, Trinity College (Biology), 1980

MS, University of Rhode Island (Zoology), 1983

PhD, Boston University (Biology), 1986

Fellowship, Stanford University School of Medicine (Neurobiology), 1990

Titles and Academic Titles


Professor of Pediatrics

Professional Memberships

Faculty of 1000, 2015-

Society for Neuroscience

American Epilepsy Society

Professional Awards

Milken Family Foundation Award, American Epilepsy Society, 1993

Basic Science Epilepsy Research Recognition Award, 201

Publication Highlights

Kahn J, Port R, Yue C-Y, Takano H, Coulter DA. Circuit-based interventions in the dentate gyrus rescue epilepsy-associated cognitive dysfunction. Brain. 2019 Sep; 142(9):2705-2721. doi: 10.1093/brain/awz209
Tang S#, Terzic B#, Wang IJ, Sarmiento N, Sizov K, Cui Y, Takano H, Marsh ED, Zhou Z*, Coulter DA*. Altered NMDAR signaling underlies autistic-like features in mouse models of CDKL5 Deficiency Disorder. Nature Communications. 2019 Jun; 10(1):2655. doi: 10.1038/s41467-019-10689-w; #=equal contributions, *=co-corresponding authors
Dengler CG, Yue C, Takano H, Coulter DA. Massively augmented hippocampal dentate granule cell activation accompanies epilepsy development. Sci. Rep. 2017 Jan; 7: 42090. PubMed PMID: 28218241
Coulter DA, Steinhäuser C. Role of astrocytes in epilepsy. Cold Spring Harb Perspect Med. 2015 Jan; 5(3):a022434. PMID: 25732035
Goldberg, EM, Coulter DA. Mechanisms of epileptogenesis: a convergence on neural circuit dysfunction. Nature Reviews in Neuroscience. 2013 Jan; 14(5):337-49. PMID: 23595016

Links of Interest