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Cornerstone Blog
CHOP Researchers Pioneer Gene Therapy to Treat XLSA in a Preclinical Model
Published on
Jan 14, 2025
In a preclinical model, the team reversed symptoms of X-linked sideroblastic anemia, a rare disorder.
Cornerstone Blog
Can Endothelial Cells Lining Veins In Lungs Help Repair Injured Blood Vessels?
Published on
Dec 16, 2024
Dr. David Frank and a team of researchers found that pulmonary venous endothelial cells contribute to the repair of blood vessels after lung injury.
Cornerstone Blog
Could Benefits Outweigh Risks of Vaccinating NICU Patients Against Rotavirus?
Published on
Dec 10, 2024
A Snapshot Science sums up how researchers explored rates of vaccine-strain rotavirus transmission in CHOP’s neonatal intensive care unit.
Cornerstone Blog
Could DLK1 Be an Immunotherapeutic Target to Treat Neuroblastoma?
Published on
Nov 6, 2024
Researchers identify cell surface protein DLK1 as a potential immunotherapeutic target for neuroblastoma.
Cornerstone Blog
What Are the Genomic Drivers of Childhood T-ALL?
Published on
Sep 30, 2024
CHOP researchers uncovered 15 subtypes of T-cell acute lymphoblastic leukemia, which will help to predict outcomes and guide treatment.
Cornerstone Blog
How Can We Improve Gene Therapy to Treat Hemophilia A?
Published on
Sep 19, 2024
CHOP researchers developed a factor VIII variant that led to safe and long-lasting therapeutic results in preclinical models.
Cornerstone Blog
Can High-Throughput Assays Help Classify Uncertain Variants?
Published on
Aug 15, 2024
In this Snapshot Science, researchers use high-throughput assays to characterize thousands of variants associated with Alagille syndrome.
Cornerstone Blog
Is Selpercatinib Safe, Effective for Children With RET-altered Solid Tumors?
Published on
Aug 5, 2024
Selpercatinib is the first targeted cancer therapy for pediatric patients 2 years of age and older with RET gene alterations.
Cornerstone Blog
Can Clinicians Use T Cells to Detect Early-Stage Cancers?
Published on
Jul 15, 2024
CHOP researchers identify biomarkers for early detection of high-grade ovarian cancer.
Cornerstone Blog
Can Sleep Promotion Help Lower Hypertension in Children?
Published on
Jun 27, 2024
Sleep promotion, along with diet and exercise, may be another non-pharmacologic option to help reduce hypertension in pediatric patients.
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