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Cornerstone Blog
How Does Chemotherapy Affect the Neuroblastoma Tumor-Immune Cell Microenvironment?
Published on
May 7, 2025
Using advanced omics and computational techniques, the researchers found that both cancer and immune cells changed after treatment.
Cornerstone Blog
Could a Novel ‘Trojan Horse’ Prodrug Approach be Effective in Treating Malaria?
Published on
Mar 6, 2025
Study results from the John Lab reveal how a novel “Trojan horse” prodrug strategy could help researchers design treatments that more effectively combat malaria.
Cornerstone Blog
Could an In Vivo Gene Therapy Strategy be Effective in Treating Fanconi Anemia?
Published on
Feb 24, 2025
A pre-clinical study sets the stage for medical advances: A gene therapy treatment approach for Fanconi anemia patients.
Cornerstone Blog
What Is the Metabolic Mechanism of Brain Functional Development During Infancy?
Published on
Jan 29, 2025
This Snapshot Science reveals how cerebral blood flow maps indicate an emergence of physiological cortical hierarchy during infancy.
Cornerstone Blog
Can Gene Therapy Improve Long-term Cardiac Outcomes for Patients with Danon Disease?
Published on
Jan 27, 2025
Early Phase 1 trial results show potential for gene therapy to improve long-term cardiac outcomes.
Cornerstone Blog
What is the Role of MHC-I Proteins in Immune Surveillance?
Published on
Jan 20, 2025
CHOP researchers are the first to capture a structural snapshot of an MHC-I molecule as it screened for peptides, a critical immune system process.
Cornerstone Blog
CHOP Researchers Pioneer Gene Therapy to Treat XLSA in a Preclinical Model
Published on
Jan 14, 2025
In a preclinical model, the team reversed symptoms of X-linked sideroblastic anemia, a rare disorder.
Cornerstone Blog
Can Endothelial Cells Lining Veins In Lungs Help Repair Injured Blood Vessels?
Published on
Dec 16, 2024
Dr. David Frank and a team of researchers found that pulmonary venous endothelial cells contribute to the repair of blood vessels after lung injury.
Cornerstone Blog
Could Benefits Outweigh Risks of Vaccinating NICU Patients Against Rotavirus?
Published on
Dec 10, 2024
A Snapshot Science sums up how researchers explored rates of vaccine-strain rotavirus transmission in CHOP’s neonatal intensive care unit.
Cornerstone Blog
Could DLK1 Be an Immunotherapeutic Target to Treat Neuroblastoma?
Published on
Nov 6, 2024
Researchers identify cell surface protein DLK1 as a potential immunotherapeutic target for neuroblastoma.
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