16BT052; Unrelated And Partially Matched Related Donor PSCT w/ TCR αβ depletion for patients with BMF



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The purpose of this research study is to test a new method of cell processing for stem cell transplants with an unrelated donor or partially matched related donor for patients with BMF who do not have a well matched related donor. The new method is called alpha/beta T cell and B cell depletion using a device called CliniMACs.  We want to see if this method can reduce some of the complications of the transplant and decrease the time it takes for the new stem cells to establish a new immune system.

Who Do I Contact?

If you are interested in participating in the study or want to learn more please contact our study team at mcglynn [at] chop.edu or 215-590-1303.

Eligibility & Criteria

IRB #:
Official Title:
16BT052- Unrelated And Partially Matched Related Donor Peripheral Blood Stem Cell Transplantation With TCR αβ + T Cell And B Cell Depletion For Patients With Acquired And Inherited Bone Marrow Failure
Study Phase:
Not Applicable
Eligible Age Range:
0 - 25 Years
Study Categories: