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Results for Bone Marrow Transplant

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Timothy S. Olson, MD, PhD
Timothy S. Olson Headshot

Dr. Olson aims to improve diagnostics and treatment of bone marrow failure (BMF) syndromes, and to improve clinical hematopoietic stem cell transplantation (HSCT) outcomes. He conducts clinical trials of HSCT for non-malignant hematologic diseases. His laboratory explores both basic and translational research focused on genomics of BMF and the impact of BMF on hematopoietic niche function during HSCT.

E-mail:
olsont [at] chop.edu
Nancy J. Bunin, MD

Dr. Bunin's current research focuses on the development of hematopoietic stem cell graft engineering for allogeneic transplantation to minimize graft-versus-host disease (GVHD), promote engraftment and immune reconstitution. She has also developed protocols for rapid manufacture of viral cytotoxic T lymphocytes to treat or prevent life threatening viral infections post hematopoietic stem cell transplant.

E-mail:
buninn [at] chop.edu
Benjamin L. Laskin, MD, MS
Benjamin L. Laskin

Dr. Laskin's research focuses on the conduct of clinical investigations and translational studies designed to target mechanisms to prevent, treat, or slow the progression of chronic kidney disease in immunosuppressed patients, including children receiving a bone marrow or kidney transplant.

E-mail:
laskinb [at] chop.edu
Peter Kurre, MD
Peter Kurre

Dr. Kurre's laboratory has longstanding expertise in Fanconi Anemia (FA), a genetic condition with prominent hematologic complications. With training in transplantation and hematopoietic stem cell biology, he hopes to improve the understanding of the progressive hematopoietic failure in patients with bone marrow failure and FA, broaden diagnostic approaches, and develop next generation therapies.

E-mail:
kurrep [at] chop.edu
Stephan A. Grupp, MD, PhD
Stephan A. Grupp

Dr. Grupp develops and conducts preclinical testing of engineered cell therapies and signal transduction inhibitors in leukemia, in pediatric immunotherapy trials, and in the manufacture and use of cellular therapeutics in preclinical, good manufacturing practices, and clinical trial settings. Dr. Grupp leads most CTL019 (CD19 CAR) clinical trials, and his colleagues are the global leaders in highly active CAR T cell therapy.

E-mail:
grupp [at] chop.edu
Jason L. Freedman, MD, MSCE
Jason L. Freedman

Dr. Freedman has a particular interest in epidemiologic and translational research within pediatric supportive oncology. He aims to advance the understanding and treatment of symptoms, infections, and organ toxicities in pediatric cancer and hematopoietic stem cell transplant patients.

E-mail:
freedmanj [at] chop.edu
Sogol Mostoufi-Moab, MD, MSCE
Sogol Mostoufi-Moab Headshot

Dr. Mostoufi-Moab's clinical and research program is focused on endocrine late effects after childhood cancer therapy. She has unique dual training in pediatric endocrinology and oncology with a master's degree in clinical epidemiology. The goal of her research program is to pursue a mechanistic understanding of metabolic and endocrine disorders that occur due to cancer therapy.

E-mail:
moab [at] chop.edu

In The News: Football Concussions, Early Intervention Referrals, Mitochondrial DNA, Panama TV, ‘Research in Motion,’ Bone Marrow Failure

Published on
Oct 23, 2020
in Cornerstone Blog
In the News
This week’s roundup features research reinforcing the need for better universal surveillance for developmental delays and increased access to early intervention. This and more In The News.

CHOP Physician-Scientist in Search of Cure for Fanconi Anemia

Published on
Oct 15, 2020
in Cornerstone Blog
CHOP Physician-Scientist in Search of Cure for Fanconi Anemia
Peter Kurre, MD, seeks to determine to what extent defects in fetal blood forming cells accelerate the loss of bone marrow function in young patients.

Exploring Exosome-Mediated Stem Cell Engraftment for Hemoglobinopathies

Published on
May 8, 2019
in Cornerstone Blog
Meghana V. Kashyap, MD
A surgeon-scientist explores exosome-mediated stem cell engraftment as a means to lessen disease severity and enhance quality of life for children with hemoglobinopathies.
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In this section

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In this section

Filter By

  • Principal Investigator / Faculty (7)

Organizations

  • Comprehensive Bone Marrow Failure Center (6)
  • Department of Pediatrics (6)
  • Division of Oncology (5)
  • Division of Hematology (3)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (2)
  • Cancer Immunotherapy (CAR-T) (1)
  • Center for Childhood Cancer Research (1)
  • Center for Injury Research and Prevention (1)
  • Division of Developmental and Behavioral Pediatrics (1)
  • Division of Endocrinology and Diabetes (1)
  • Division of Gastroenterology, Hepatology, and Nutrition (1)
  • Division of Nephrology (1)
  • Mitochondrial Medicine (1)
  • Normal and Malignant Hematopoiesis Research Affinity Group (1)
  • PolicyLab (1)
  • Rivella Laboratory (1)
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