Neuroblastoma | CHOP Research Institute
 

Neuroblastoma

22CT012: GPC2 CAR T Cell Trial

The purpose of this study is to test an experimental approach called cell therapy for neuroblastoma or retinoblastoma.

Cornerstone Blog

Drug-Diet Combo Reduces Tumor Growth in Childhood Cancer Models, CHOP Study Finds

Published on
Sep 24, 2025
Drug-Diet Combo Reduces Tumor Growth in Neuroblastoma Models
Preclinical findings offer a potential new strategy for treating high-risk neuroblastoma.
Cornerstone Blog

Precision Medicine, Smoking Intervention, Pediatric Solid Tumors, Dental Health

Published on
Sep 19, 2025
Precision Medicine; Smoking Intervention; Pediatric Solid Tumors; Dental Health
Scientists advance precision medicine approaches to ALK-driven cancers and pediatric solid tumors and give insights for preventive dentistry.
Cornerstone Blog

How Does Chemotherapy Affect the Neuroblastoma Tumor-Immune Cell Microenvironment?

Published on
May 7, 2025
CHOP Researchers Create Cell Atlas of High-Risk Neuroblastoma
Using advanced omics and computational techniques, the researchers found that both cancer and immune cells changed after treatment.
Cornerstone Blog

CHOP-developed Drug for High-risk Tumors Advances to Clinical Trials in Children

Published on
Apr 3, 2025
Garrett Brodeur
PEEL-224, a therapy to treat high-risk tumors, enters a pediatric clinical trial after a decade of groundbreaking research.

PEEL-224 in Solid Tumors

This study enrolls patients with refractory, progressive, or relapsed solid tumors.

Cornerstone Blog

Dr. Evans’ Legacy, Fellows of the AACR Academy, Novel Gene Therapy Approach for MLD

Published on
Mar 21, 2025
Dr. Evans’ Legacy, AACR Fellows, Novel Gene Therapy Approach for MLD
This week’s In The News highlights the legacy of Dr. Audrey Evans, newly elected AACR fellows, and a novel approach for rare disease.
Cornerstone Blog

Alex’s Lemonade Stand Powers 20 Years of Pediatric Cancer Research at CHOP

Published on
Dec 19, 2024
Alex’s Lemonade Stand and CHOP: A 20-year Collaboration
As the pediatric cancer charity celebrates its 20th anniversary, Cornerstone is highlighting the groundbreaking research at CHOP fueled by two decades of collaboration.
Cornerstone Blog

Uncovering the Genetic Connection Between Birth Defects and Childhood Cancers

Published on
Dec 5, 2024
At the Intersection of Birth Defects and Childhood Cancers
CHOP researchers are looking to enhance the understanding of the possible genetic links between childhood cancers and structural birth defects.
Cornerstone Blog

Excellence Award, Orphan Drug Designation, Imaging Technique, Coordinated Asthma Care

Published on
Nov 22, 2024
Excellence Award, Rare Disease, Orthopedic Ultrasound
Congratulations to physician scientist Dr. Yael Mosse, who received a Penn Medicine Award of Excellence for her contributions to pediatric oncology, and more.