T Cells | CHOP Research Institute

In the News: Outstanding Science Award, Highly Cited Researcher, STAT Wunderkinds

Published on

Dec 9, 2022

This week's news roundup features an outstanding science award, Highly Cited Researchers, and STAT Wunderkinds, along with new research about cancer risk with birth defects, epilepsy, and acute myeloid leukemia.

Will Bailis, PhD

Dr. Bailis aims to understand how metabolism underlies immunology and disease, by controlling the biochemistry of cells and tissues. His lab does so using in vitro and in vivo CRISPR engineering of primary human and mouse immune cells, with the goal of developing diet and metabolite based therapies.

E-mail:

bailisw [at] chop.edu

Oliver Laboratory

The Oliver Lab focuses on revealing mechanisms governing T cell activation and protective immunity. Its goal is to define mechanisms that, when dysregulated, result in autoimmunity or allergic disorders like asthma.

Bailis Laboratory

All biological processes operate under biochemical constraints. The Bailis Lab aims to understand how metabolism controls the development and functional differentiation of the hematopoietic system by setting the biochemical potential of cells and tissues, using in vitro and in vivo CRISPR screening in primary immune cells.

Snapshot Science: Can T Cells From Lymphatic Fluid Benefit CAR T-Cell Therapy?

Published on

Oct 7, 2020

in Cornerstone Blog

Researchers used T Cells from the lymphatic fluid instead of blood for CAR T-Cell therapy.

Cancer Immunotherapy (CAR-T)

Shifting the paradigm to treat the toughest pediatric cancers with new cell therapies that reprogram a patient's own immune system to kill cancer cells.

On the Road to Better Treatments for Obese Asthmatics

Published on

Apr 17, 2019

in Cornerstone Blog

Sarah Henrickson, MD, PhD, receives new grant to uncover possible causes to immune system dysfunction in hard-to-treat obese asthmatics.

In the News: Sleep Problems and Autism, Opioid Overprescription, Food Pharmacy, Gun Violence Prevention, Proof-of-Concept Award, and Lung Cells in Fetal Development

Published on

Feb 22, 2019

in Cornerstone Blog

Balancing analgesia and opioid stewardship — two priorities of orthopedic surgeons. Research by Apurva Shah, MD, shows opioid overprescription.

Paula M. Oliver, PhD

Dr. Oliver investigates the mechanisms governing T cell activation and protective immunity. Her goal is to define mechanisms that, when dysregulated, result in autoimmunity or allergic disorders like asthma.

E-mail:

oliverp1 [at] chop.edu

In the News: Study Tops Most-Read List, the Migratory T Cell Response, Mossé Named Endowed Chair, ‘Healthier Together’ Launches, Supporting Survivors

Published on

Dec 28, 2018

in Cornerstone Blog

In this week’s roundup, CHOP launches a partnership to help the most vulnerable kids with asthma, and research supports a holistic approach to recovery from violence.