Mitochondrial Medicine

Cornerstone Blog

Dietary Fats, Reducing Concussion in Football, Biomedical Award

Published on

Sep 5, 2025

Dietary Fats, Reducing Concussion in Football, Biomedical Award

Researchers uncover a link between dietary fats and severe forms of asthma, and a study shares results of safety equipment to reduce concussion at a professional level.

Mitochondria and Cancer Connections (MC²) Research Program

The Mitochondria and Cancer Connections (MC²) Research program leverages knowledge from existing centers to establish a novel, cutting-edge research initiative and enable the development of mechanistic understanding and novel therapeutic opportunities at the intersection of mitochondrial disease and pediatric cancer.

Astellas Clinical Trial for ASP0367

We are recruiting patients with genetically confirmed primary mitochondrial myopathy who are at least 18 years old for a randomized, double-blind, placebo-controlled study of a new drug to treat this disorder.

Cornerstone Blog

MC² Program Energizes Research Between Mitochondrial Disease and Pediatric Cancer

Published on

Sep 22, 2021

MC² Program Energizes Research Between Mitochondrial Disease and Pediatric Cancer

Marni Falk, MD, and Adam Resnick, PhD, to lead the Mitochondria and Cancer Connections (MC²) Research Program, a new CHOP research initiative.

DCA Trial in PDC Deficiency

We are studying an investigational drug called sodium dichloroacetate (DCA).

Mitochondrial Medicine Research Group Laboratory

The Mitochondrial Medicine Research Laboratory investigates the genetic etiologies, pathophysiologic mechanisms, and therapeutic targets of mitochondrial disease. The lab applies state-of-the-art technologies and approaches in diverse animals (C. elegans worms, D. rerio zebrafish, M.

The Resuscitation Science Center

The Resuscitation Science Center is a multifaceted, collaborative scientific platform dedicated to understanding critical illnesses and accelerating discoveries to improve resuscitation care and outcomes for children. By partnering translational and clinical science, the Center takes a true bench-to-bedside approach to pediatric research.

Ganetzky Laboratory

The Ganetzky Lab focuses on inherited mitochondrial respiratory chain disorders with a goal of applying biochemical approaches to develop improved diagnostic modalities, especially for mitochondrial Complex V (ATP Synthase) deficiency.

Rebecca D. Ganetzky, MD

Dr. Ganetzky is passionate about developing new biochemical strategies for accurate diagnosis and classification of inborn errors of energy metabolism. She has a particular focus on diseases of mitochondrial complex V (ATP Synthase).

E-mail:

ganetzkyr [at] chop.edu

Marni J. Falk, MD

Dr. Falk is a Clinical Geneticist who serves as executive director of the Mitochondrial Medicine Frontier Program. Her translational research lab investigates the causes and global metabolic consequences of mitochondrial disease, as well as targeted therapies, in C. elegans, zebrafish, mouse, and human tissue models of genetic-based respiratory chain dysfunction.

E-mail:

falkm [at] chop.edu