Sepsis | CHOP Research Institute
 

Sepsis

The study will use residual blood collected from clinical samples collected around the time of meeting study inclusion to identify subphenotypes of subjects with shared underlying protein biomarker profiles, correlate subphenotypes with PICU morality, and assess degree of overlap between subphenotypes and classical syndromic definitions.

The LUng iNjury Group at Children's Hospital of Philadelphia is dedicated to advancing the care of children who have difficulty breathing, with a focus on hospitalized children with severe respiratory failure requiring mechanical ventilation.

The Immunology and Infectious Disease Research Initiative will harness the depth and breadth of infectious disease and immunology research across Children’s Hospital of Philadelphia to become the global leader in the study of infectious disease, vaccinology, and immunology.

Jenny Bush, BSN, RN is the clinical research nurse lead of the Critical Care Medicine research team within the Department of Anesthesiology and Critical Care medicine.

E-mail:
BushJ1 [at] chop.edu
Published on
Apr 2, 2024
CHOP researchers from Emergency Medicine and Arcus are co-leading a project to develop a national pediatric sepsis surveillance definition.
Published on
Feb 26, 2024
Dr. Brad Lindell explains how the Junior Faculty Award allowed his lab to build a large multi-omics sepsis dataset that may help researchers identify novel proteomic signatures related to high-risk adverse events.
Published on
Dec 8, 2023
Our research news roundup highlights the improvements made in CAR therapies through structural biology discoveries and cost reduction strategies.
Published on
Nov 20, 2023
The NIH-funded study, PRESCRIBE, will help researchers understand how antibiotics affect organ function recovery and respiratory microbiota in children with sepsis.

The overall goal of the Lindell Lab is to leverage translational immunology to define “treatable traits” in pediatric sepsis patients which can inform novel approaches to precision immunomodulation.

Published on
Jun 28, 2023
Kandace Gollomp, MD, attending physician in the Division of Hematology, studies neutrophils to understand how they interact with infections.