Stem Cells | CHOP Research Institute

Cornerstone Blog

College of Physicians, Predictive Modeling, Nanopore Sequencing, Crohn’s Disease

Published on

Oct 31, 2025

College of Physicians, Predictive Modeling, Nanopore Sequencing

A multi-institutional study results in improved machine learning predictive modeling for sepsis risk and more in this week’s research news.

Qian Laboratory for Human Cerebral Cortex Development

The Qian Lab studies human cerebral cortex development and disease using brain organoids, spatial omics, and genetics to uncover mechanisms of normal development and neurodevelopmental disorders, with the goal of enabling human-specific therapeutic insights.

Xuyu Qian, PhD

Dr. Xuyu Qian investigates the development and diseases of the human cerebral cortex to elucidate the underpinnings of normal brain development and neurodevelopmental disorders. His research integrates spatial omics, brain organoids, and genetics to overcome limitations of traditional models.

E-mail:

qianx [at] chop.edu

Cornerstone Blog

Immune Memory, Tuberculosis Screening, Nursing Lifetime Achievement

Published on

Apr 4, 2025

Discover how acute myeloid leukemia could alter the immune memory of healthy cells among other stories in this week’s research news.

Cornerstone Blog

At the Forefront of Breakthroughs: Cell and Gene Therapy Lab Sets Course for Expansion

Published on

Jan 12, 2024

Cell and Gene Therapy Laboratory Prepares to Expand

The Cell and Gene Therapy Lab at CHOP has been approved for a phased expansion project that will allow them to keep up with the pace of discovery in a rapidly changing field.

Cornerstone Blog

Can a Small Molecule Drug Improve Cell Fitness for Transplantation?

Published on

Oct 20, 2023

Snapshot Science: Can a Drug Improve Cells for Transplantation?

Researchers found exposing cells to a small molecule drug improves cell fitness during hematopoietic stem cell transplants, which could improve ex vivo gene therapy.

Thom Lab

The Thom Lab, an integrated genomics and cell biology lab, aims to define novel factors that regulate blood cell development and function in order to augment in vitro blood cell production.

Phase II Mayo Clinic Stem Cell Trial for HLHS

The purpose of this research study is to find out if stem cells from umbilical cord blood can strengthen the muscle of the right side of the heart for patients diagnosed with Hypolplastic Left Heart Syndrome who are scheduled to undergo the Stage II Glenn surgical procedure.

Gadue Laboratory

The Gadue Lab studies human pancreatic and hematopoietic development and associated diseases using human pluripotent stem cells. The lab’s research efforts are devoted to directed differentiation and CRISPR-based genome engineering of stem cells to use in the study and development of treatments for diabetes and blood disorders.

Fetal Biology and Therapy Research Affinity Group

Exploring the possibilities for treating disorders during fetal development.