The Cell and Gene Therapy Lab at CHOP has been approved for a phased expansion project that will allow them to keep up with the pace of discovery in a rapidly changing field.
Researchers found exposing cells to a small molecule drug improves cell fitness during hematopoietic stem cell transplants, which could improve ex vivo gene therapy.
The Thom Lab, an integrated genomics and cell biology lab, aims to define novel factors that regulate blood cell development and function in order to augment in vitro blood cell production.
The purpose of this research study is to find out if stem cells from umbilical cord blood can strengthen the muscle of the right side of the heart for patients diagnosed with Hypolplastic Left Heart Syndrome who are scheduled to undergo the Stage II Glenn surgical procedure.
The Gadue Lab studies human pancreatic and hematopoietic development and associated diseases using human pluripotent stem cells. The lab’s research efforts are devoted to directed differentiation and CRISPR-based genome engineering of stem cells to use in the study and development of treatments for diabetes and blood disorders.
Stefano Rivella, PhD, is developing a novel gene therapy that could help patients living with sickle cell disease and other debilitating red blood disorders.
