Proteomics | CHOP Research Institute


Published on
Aug 8, 2023
Two CHOP researchers receive the Individual Biomedical Research Award from the Hartwell Foundation, which will fund early-stage, innovative projects.

The Single Cell Technology Core specializes in state-of-the-art single cell technologies and the analysis of complex data sets. We facilitate transcriptomic, epigenomic, and spatial-omic experiments.

Research in the Weitzman Lab aims to understand host responses to virus infection, and the cellular environment encountered and manipulated by viruses. The lab studies multiple viruses in an integrated experimental approach that combines biochemistry, molecular biology, genetics, and cell biology.

The research objectives of the Ischiropoulos Lab are to elucidate the nitric oxide signaling pathways at the proteome level in the cardiovascular and neuronal systems; define the molecular mechanisms by which nitric oxide signaling regulates metabolic pathways during development and aging; and develop and test novel therapeutics for long-chain f

The CHOP-Penn Proteomics Core provides a variety of protein and proteomics services for investigators at Children’s Hospital of Philadelphia, University of Pennsylvania, and outside institutions.

Dr. Ischiropoulos's research objectives are to develop and test novel therapeutics for long-chain fatty acid oxidation (LCFA) disorders, a collection of inherited metabolic diseases that affect the heart, liver and muscle. A second area of interest is the resolution of the nitric oxide signaling pathways at the proteome level in the cardiovascular and neuronal systems.

ischirop [at]

Dr. Diskin's research is focused on translational genomics in childhood cancers. Her laboratory seeks to identify the genetic basis of childhood cancers by combining quantitative computational methods with rigorous "wet-lab" experimental approaches. In parallel, she has developed, and is applying, a proteogenomic approach to identify novel immunotherapeutic targets for high-risk and relapsed pediatric malignancies.

diskin [at]
Published on
Nov 13, 2018
Synthesizing diverse data sets from many sources comes with vast opportunities to change pediatric medicine.