Lysosomes | CHOP Research Institute
 

Lysosomes

The Marks Lab aims to dissect the molecular mechanisms underlying the formation of cell type-specific lysosome-related organelles and the assembly, delivery, and function of their contents, and to understand how these processes are impacted by genetic diseases.

Published on
Nov 11, 2020
Michael Marks, PhD, seeks to identify the genetic basis of normal human skin pigment variation, which could offer disease insight.
Published on
Dec 4, 2019
John Wolfe, VMD, PhD, receives grant to study gene therapy treatment for lysosomal storage disorders with severe disease of the brain.

Dr. Marks investigates the molecular mechanisms underlying the formation of cell type-specific lysosome-related organelles; the assembly, delivery and function of their contents; and how these processes are impacted by genetic diseases.

E-mail:
marksms [at] chop.edu

Dr. Akizu’s research focuses on genetic and epigenetic mechanisms of neurodevelopmental disorders and pediatric neurodegeneration, with the specific goals of uncovering particularities mechanisms that provide diversity to the human brain and to uncover novel disease mechanisms and therapeutic options.

E-mail:
aquizun [at] chop.edu