In This Section

Contact
E-mail
gottardi [at] email.chop.edu
Twitter Handle
Location - People View
Room 1015F

3615 Civic Center Blvd
Philadelphia, PA 19104
United States

Research Topics
Riccardo L. Gottardi, PhD
Riccardo L. Gottardi
Research Scientist

Dr. Gottardi leads the Bioengineering and Biomaterials (Bio2) lab, collaborating on clinical and research efforts to offer engineering solutions for pediatric health, primarily treatments for airway disorders. Dr. Gottardi researches mechanisms of laryngotracheal pathologies, applies tissue engineering to improve pediatric conditions, develops new devices, and formulates controlled drug delivery systems to treat and improve patients’ lives.

AddtoAny

Bio

Dr. Riccardo Gottardi graduated in 2003 in Applied Physics at the University of Pisa and obtained his PhD in 2007 from the University of Genova (Italy) working on a collaborative project with the Biozentrum of the University Basel (Switzerland, Prof. Ueli Aebi) on atomic force microscopy-based multiscale early diagnosis of osteoarthritis in knee articular cartilage.

In 2011 he moved to the University of Pittsburgh thanks to a fellowship from the Ri.MED Foundation to work in the Center for Cellular and Molecular Engineering of the Department of Orthopaedic Surgery with Dr. Rocky S. Tuan, and in the Little Laboratories of the Department of Chemical and Petroleum Engineering with Dr. Steven R. Little. His research focused on tissue engineering/regenerative medicine of cartilage and joint soft tissues and on the application of nanotechnology to drug delivery and cellular guidance for tissue repair.

In 2017 he became research assistant professor in the Department of Orthopaedic Surgery of the University of Pittsburgh, where he developed innovative synthetic tissue models to study tissue cross talks in health and disease. He was recognized by the Foundation for Women’s Wellness for his research on hormones and osteoarthritis, he led a research effort to study bone loss taking advantage of the unique microgravity environment on the International Space Station, and developed a research program in regenerative rehabilitation, using rehabilitation regimens to mechanobiologically activate and guide joint tissue repair.

Since January 2019, Dr. Gottardi has lead Children’s Hospital of Philadelphia’s Bioengineering and Biomaterials laboratory, the first pediatric lab of its kind initiated through the Frontiers Programs. While collaborating on tissue engineering and controlled drug delivery across CHOP, the lab is especially focused on engineering solutions for airway disorders, on biomaterials for laryngotracheal cartilage engineering, and on approaches to prevent and repair damage to the vocal folds.

Education and Training

BSc, University of Pisa, Italy (General Physics), 2003

MSc, University of Pisa (Applied Physics) 2003

PhD, University of Genova (Biomedical Engineering), 2007

Titles and Academic Titles

Research Scientist

Professional Memberships

International Cartilage Repair Society, 2010-

American Institute of Chemical Engineering, 2012-

Biomedical Engineering Society, 2012-

Tissue Engineering and Regenerative Medicine, 2013-

Orthopaedic Research Society, 2016-

Professional Awards

Travel Award to attend AAOS/CORR/ORS/CMH-UCD/SWHR Musculoskeletal Sex Differences Throughout the Lifespan Research Symposium, 2014

First prize at the Penn Orthopaedics 2015 Cartilage Repair Symposium, 2015

Iris Klarman Women’s Health Fellowship Award from the Foundation for Women’s Wellness, 2016

Pitt Innovator Award, 2016

Young Investigator Award at the 2nd Fusion Conference on Musculoskeletal Development and Regeneration Conference, 2017

Travel Award to attend AAOS/ORS The Physis: Fundamental Knowledge to a Fantastic Future through Research, 2018

 

Publication Highlights

Gottardi R, Stoddart MJ. Regenerative rehabilitation of the musculoskeletal system. J Am Acad Orthop Surg. 2018 Aug; 26(15):e321-e323. doi: 10.5435/JAAOS-D-18-00220.. PMID: 29985246
Nichols DA, Sondh IS, Little SR, Zunino P, Gottardi R. Design and validation of an osteochondral bioreactor for the screening of treatments for osteoarthritis. Biomed Microdevices. 2018 Feb; 20: 18. DOI: 10.1007/s10544-018-0264-x. PMID: 29445972
Gottardi R, Hansen U, Raiteri R, Loparic M, Düggelin M, Mathys D, Friederich NF, Bruckner P, Stolz M. Supramolecular organization of collagen fibrils in healthy and osteoarthritic human knee- and hip joint cartilage. PLoS ONE. 2016 Oct; 11(10): e0163552. DOI: 10.1371/journal.pone.0163552. PMID: 27780246
Kamalasanan K, Gottardi R, Tan S, Chen Y, Godugu B, Rothstein S, Balazs AC, Star A, Little SR. “Zero Dimensional” Single Walled Carbon Nanotubes. Angew Chem Int Ed Eng. 2013 Oct; 52(43):11308-12.DOI: 10.1002/anie.201305526. PMID: 24038731
Stolz M, Gottardi R, Raiteri R, Miot S, Martin I, Imer R, Staufer U, Raducanu A, Düggelin M, Baschong W, Daniels AU, Friederich NF, Aszodi A, Aebi U. Early detection of osteoarthritic and aging articular cartilage in mice and patient samples using AFM. Nat Nanotechnol. 2009 Mar; 4(3):186-92.DOI: 10.1038/nnano.2008.410. PMID: 19265849

Links of Interest