Academic Department: 
Pediatrics
Division: 
Pulmonary Medicine
Job Title(s): 
Research Scientist
Office Location: 

Abramson Research Center, 1015F

Affiliations

Bioengineering and Biomaterials Lab

Bio

Dr. Riccardo Gottardi graduated in 2003 in Applied Physics at the University of Pisa and obtained his PhD in 2007 from the University of Genova (Italy) working on a collaborative project with the Biozentrum of the University Basel (Switzerland, Prof. Ueli Aebi) on atomic force microscopy-based multiscale early diagnosis of osteoarthritis in knee articular cartilage. In 2011 he moved to the University of Pittsburgh thanks to a fellowship from the Ri.MED Foundation to work in the Center for Cellular and Molecular Engineering of the Department of Orthopaedic Surgery with Dr. Rocky S. Tuan, and in the Little Laboratories of the Department of Chemical and Petroleum Engineering with Dr. Steven R. Little. His research focused on tissue engineering/regenerative medicine of cartilage and joint soft tissues and on the application of nanotechnology to drug delivery and cellular guidance for tissue repair. In 2017 he became Research Assistant Professor in the Department of Orthopaedic Surgery of the University of Pittsburgh where he developed innovative synthetic tissue models to study tissue cross talks in health and disease. He was recognized by the Foundation for Women’s Wellness for his research on hormones and osteoarthritis, he led a research effort to study bone loss taking advantage of the unique microgravity environment on the International Space Station, and developed a research program in regenerative rehabilitation, using rehabilitation regimens to mechanobiologically activate and guide joint tissue repair.

Since January 2019 Dr. Gottardi is leading the CHOP Bioengineering and Biomaterials laboratory, the first pediatric lab of its kind initiated through the Frontiers Programs. While collaborating on tissue engineering and controlled drug delivery across CHOP, the lab is especially focused on engineering solutions for airway disorders, on biomaterials for laryngotracheal cartilage engineering, and on approaches to prevent and repair damage to the vocal folds.

Research Focus
Education/Training

2003                        B. Sc., University of Pisa, Pisa, Italy, General Physics
2003                        M. Sc., University of Pisa, Pisa, Applied Physics
2007                        Ph.D., University of Genova, Genova, Biomedical Engineering

Professional Memberships

2016-present            ORS – Orthopaedic Research Society
2013-present            TERMIS – Tissue Engineering and Regenerative Medicine
2012-present            BMES – Biomedical Engineering Society
2012-present            AIChE – American Institute of Chemical Engineering
2010-present            ICRS – International Cartilage Repair Society
2008-2011                 ESB – European Society of Biomechanics

Professional Awards

2018                         Travel Award to attend AAOS/ORS The Physis: Fundamental Knowledge to a Fantastic Future
                                  through Research
2017                         Young Investigator Award at the 2nd Fusion Conference on Musculoskeletal Development and
                                  Regeneration Conference
2016                         Iris Klarman Women’s Health Fellowship Award from the Foundation for Women’s Wellness
2016                         Pitt Innovator Award
2015                         First prize at the Penn Orthopaedics 2015 Cartilage Repair Symposium
2014                         Travel Award to attend AAOS/CORR/ORS/CMH-UCD/SWHR Musculoskeletal Sex Differences
                                  Throughout the Lifespan Research Symposium
2014                         Scholarship for the course “From Benchtop to Bedside: what every scientist needs to know”,

Selected Publications

1. R. Gottardi, M. Stoddart. Regenerative rehabilitation of the musculoskeletal system. Journal of the American Academy of
   Orthopaedic Surgeons.
2018, 26(15): e321-e323, DOI: 10.5435/JAAOS-D-18-00220

2. D.A. Nichols, I.S. Sondh, S.R. Little, P. Zunino, R. Gottardi. Design and validation of an osteochondral bioreactor for the
    screening of treatments for osteoarthritis. Biomedical Microdevices. 2018, 20: 18. DOI: 10.1007/s10544-018-0264-x

3. R. Gottardi, U. Hansen, R. Raiteri, M. Loparic, M. Düggelin, D. Mathys, N.F. Friederich, P. Bruckner, and M. Stolz.
    Supramolecular organization of collagen fibrils in healthy and osteoarthritic human knee- and hip joint cartilage. PLoS
    ONE.
2016, 11(10): e0163552. DOI: 10.1371/journal.pone.0163552

4. K. Kamalasanan*, R. Gottardi*, S. Tan, Y. Chen, B. Godugu, S. Rothstein, A.C. Balazs, A. Star, S.R. Little. “Zero
    Dimensional” Single Walled Carbon Nanotubes. Angewandte Chemie. 2013, 52(43): 11308-11312. DOI:
    10.1002/anie.201305526

5. M. Stolz, R. Gottardi, R. Raiteri, S. Miot, I. Martin, R. Imer, U. Staufer, A. Raducanu, M. Düggelin, W. Baschong, A.U.
    Daniels, N. F. Friederich, A. Aszodi, U. Aebi. Early detection of osteoarthritic and aging articular cartilage in mice and
    patient samples using AFM. Nature Nanotechnology. 2009, 4:186-192. DOI: 10.1038/nnano.2008.410