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The founder and director of CHOP's Center for Fetal Diagnosis and Treatment, Dr. Adzick is an innovator in the field of fetal medicine, pursuing groundbreaking prenatal treatment for debilitating birth defects. He led the NIH-funded "Management of Myelomeningocele Study" (MOMS) at CHOP, a breakthrough research program that showed fetal surgery for spina bifida results in significantly improved outcomes.
Bio
A true innovator in the field of fetal medicine since its inception, Dr. Adzick has dedicated his career to the pursuit of groundbreaking prenatal treatment for debilitating birth defects. He has made pioneering contributions to the practice of fetal surgery, and today continues to explore cutting edge surgical treatment options for life-threatening fetal anatomic malformations such as urethral obstruction, congenital diaphragmatic hernia, congenital cystic adenomatoid malformation of the lung, and sacrococcygeal teratoma.
Dr. Adzick was the principal investigator for the National Institutes of Health (NIH) “Management of Myelomeningocele Study” (MOMS) at CHOP. This breakthrough study demonstrated that performing fetal surgery for spina bifida results in significantly improved outcomes versus conventional postnatal repair. The study represents the fruition of decades of research, much of it led by Dr. Adzick and his team, and is an example of how a once-radical idea can, through meticulous investigation, be transformed into a viable treatment for patients.
Dr. Adzick is also an active pediatric general and thoracic surgeon, and performs more than 400 operations a year. Much of his work is devoted to surgery in newborns, including repairs for congenital diaphragmatic hernia, abdominal wall defects, lung lesions and other complex conditions affecting neonates.
In addition, Dr. Adzick has a special interest and expertise in surgery for hyperinsulinism (HI) and pediatric thyroid disorders. Working closely with CHOP’s Congenital Hyperinsulinism Center, he has been instrumental in using 18 F-DOPA PET scanning technology to identify focal HI lesions in the pancreas, offering the chance of a complete surgical cure by performing partial pancreatectomy for affected patients. Dr. Adzick is also one of the nation’s most experienced surgeons in pediatric surgery to treat thyroid cancer and Graves disease, working in collaboration with CHOP’s Pediatric Thyroid Center.
Education and Training
AB, Harvard College (History and Science), 1975
MD, Harvard Medical School, 1979
MMM, Carnegie Mellon University (Medical Management), 2003
Titles and Academic Titles
Surgeon-in-Chief, Department of Surgery
Chief, General, Thoracic and Fetal Surgery
Director, Center for Fetal Diagnosis and Treatment
C. Everett Koop Endowed Chair in Pediatric Surgery
Professor of Surgery, Obstetrics and Gynecology
Professional Memberships
British Association of Paediatric Surgery
Canadian Association of Pediatric Surgery (honorary member)
Chilean Society of Obstetrics and Gynecology (honorary member)
International Fetal Medicine and Surgery Society
Pacific Association of Pediatric Surgeons
American Academy of Pediatrics
American College of Surgeons, Fellow
American Pediatric Surgical Association
American Surgical Association
Institute of Medicine, National Academy of Sciences
Professional Awards
Marshall K. Bartlett Fellowship, Massachusetts General Hospital, 1983
First Place, Young Investigators Award, Surgical Section, AAP, 1984
Schering Scholarship, American College of Surgeons, 1986
American Lung Association Research Award, 1989
National Kidney Foundation Fellowship, 1990
Focused Giving Award, Johnson and Johnson, 1990
Honorary Award, American Association of Plastic Surgeons, 1992
UCSF Surgical Residents' Teaching Award, 1993, 1995
Honorary Masters of Arts Degree, University of Penn, 1995
University of Penn Med Student Teaching Award, 1996
Australia and New Zealand Chapter of the American College of Surgeons Traveling Fellowship, 1998
Institute of Medicine, National Academy of Sciences, 1998
Presidential Cross for Contributions to the Republic of Poland, 1999
President, International Fetal Medicine and Surgery Society, 2000
Elected into the “International Order of the Smile,” 2002
Fellow, American Association for the Advancement of Science, 2003
President-at-Large, International Fetal Medicine and Surgery Society, 2011
Audrey Evans Award of Excellence, Ronald McDonald House, 2011
Community Service Award, Chai Lifeline, 2011
Charles Hunter Prize, American Gynecological and Obstetrical Society, 2012
Clinical Trial of the Year, Society for Clinical Trials (Management of Myelomeningocele Study), 2012
John Scott Legacy Medal and Premium, 2013
Samuel D. Gross Prize, 2015
Pennsylvania Bio Patient Impact Award, 2016
Publication Highlights
Links of Interest
Congenital Hyperinsulinism Center
Lilly and Dr. Adzick | Twice Born (YouTube/PBS)
To Believe: The Story of Fetal Therapy (Video/Children’s Hospital of Philadelphia)
Spina Bifida Breakthrough (Video/Children’s Hospital of Philadelphia)