Oncology | CHOP Research Institute
 

Oncology

Cornerstone Blog

‘Breakthrough’ Phase 3 Study Changes Standard of Care for Childhood B-cell Leukemia

Published on
Jan 6, 2025
Phase 3 Study Changes Standard of Care for Childhood B-cell Leukemia
The CHOP-led trial showed that blinatumomab plus chemotherapy drastically improved survival rates for patients with B-ALL.
Cornerstone Blog

Alex’s Lemonade Stand Powers 20 Years of Pediatric Cancer Research at CHOP

Published on
Dec 19, 2024
Alex’s Lemonade Stand and CHOP: A 20-year Collaboration
As the pediatric cancer charity celebrates its 20th anniversary, Cornerstone is highlighting the groundbreaking research at CHOP fueled by two decades of collaboration.

PTX-022 in the Treatment of Microcystic Lymphatic Malformations

The purpose of this study is to see if a new investigational topical (applied to the skin) formulation of sirolimus, PTX-022 (the study drug), is safe and effective in treating participants with microcystic Lymphatic Malformations.

Cornerstone Blog

Hyundai Hope On Wheels Supports Neuroblastoma Research at CHOP

Published on
Oct 30, 2024
Hyundai Hope On Wheels Supports Neuroblastoma Research
Adam Wolpaw, MD, PhD, and Timothy Spear, MD, PhD, have been awarded grants from Hyundai Hope On Wheels to improve CAR T-cell therapy.

INBRX-109 in Ewing Sarcoma and Gastrointestinal Stromal Tumor (GIST)

This study involves taking a study drug called INBRX-109.

Ruxolitinib After Hematopoietic Stem Cell Transplant (HSCT)

This study is enrolling people who have developed lung problems (called Bronchiolitis Obliterans or BO) after hematopoietic stem cell transplant (HSCT).

Cornerstone Blog

What Are the Genomic Drivers of Childhood T-ALL?

Published on
Sep 30, 2024
What Are the Genomic Drivers of Childhood T-ALL?
CHOP researchers uncovered 15 subtypes of T-cell acute lymphoblastic leukemia, which will help to predict outcomes and guide treatment.
Cornerstone Blog

Can Clinicians Use T Cells to Detect Early-Stage Cancers?

Published on
Jul 15, 2024
Can Clinicians Use T Cells to Detect Early-Stage Cancers?
CHOP researchers identify biomarkers for early detection of high-grade ovarian cancer.

Afamitresgene Autoleucel in Pediatric Subjects with MAGE-A4 Positive Tumors

Afamitresgene Autoleucel in Pediatric Subjects with MAGE-A4 Positive Tumors

This study involves an investigational cellular therapy called Afamitresgene Autoleucel.

Behavioral Oncology Program

Behavioral Oncology Program

The Behavioral Oncology Program aims to improve the medical and psychosocial outcomes and health-related quality of life in young patients and their families across the continuum of cancer care.