Clostridium Difficile | CHOP Research Institute
 

Clostridium Difficile

Published on
Aug 28, 2024
The Center for Microbial Medicine will empower researchers to turn their discoveries in the microbiome space into therapeutic products for patients.

The Center for Microbial Medicine at Children’s Hospital of Philadelphia leverages the microbiome to improve the health of children and bring personalized microbiome-based medicine from bench to bedside to every child who receives care at CHOP.

The Zackular Lab seeks to understand how interactions between the host, gut microbiota, and pathogenic microbes impact human health and disease.

Published on
Jul 21, 2023
CHOP reaches a major milestone in pediatric cancer treatments, treating its 500th patient with CAR T-cell immunotherapy. This and more in our weekly research news roundup.
Published on
Aug 31, 2022
Our featured Faculty Spotlight for August, Joseph Zackular, PhD, studies the interaction between Clostridioides difficile and microbes.

Dr. Silverman studies the fundamental aspects of early-life commensal microbes that influence immune system development and function. He discovered that the MHC-II E molecule prevents type 1 diabetes by shaping the intestinal microbiota early in life.

E-mail:
silvermam1 [at] chop.edu

Dr. Zackular's research is focused on understanding how interactions between the host, gut microbiota, and pathogenic microbes impact human health and disease. His recent efforts center on understanding how the important nosocomial pathogen, Clostridium difficile, interacts with resident gut microbiota during infection and how interspecies cross-talk impacts growth, behavior, and virulence of this pathogen.

E-mail:
zackularj [at] chop.edu