Blood Coagulation | CHOP Research Institute
 

Blood Coagulation

Dr. Kumar's research focuses on structure and function of proteins in blood coagulation. Using a coupled structural and biochemical approach, his lab studies molecular mechanisms underlying coagulation with a goal to understand how the tertiary structure determines the function of coagulation proteins

E-mail:
kumars [at] chop.edu

The Krishnaswamy Lab studies molecular mechanisms underlying the reactions of blood coagulation. The laboratory investigates how the proteins of blood coagulation interact with each other and with membranes to yield a regulated clotting response to vascular injury or an unregulated response in thrombotic or bleeding disease.

The Camire Lab is interested in understanding the components of the blood coagulation system, how they interface with activated cells, and how disturbances in their function lead to bleeding and thrombosis.

Published on
Dec 18, 2019
Sriram Krishnaswamy, PhD, receives ASH’s 2019 prestigious Ernest Beutler Lecture award and gives talk at Society’s annual meeting in Florida.
Published on
Dec 21, 2018
“The problem with too much clotting is by far one of the most staggering medical issues in the Western world,” Dr. Krishnaswamy said. See what he and his colleagues are doing to combat this deadly disease.

Dr. Camire's research focuses on understanding the components of the blood coagulation system, how they interface with activated cells, and how disturbances in their function lead to bleeding and thrombosis. He is also interested in developing novel therapeutic approaches (protein, gene-based, small molecule) to mitigate these events, which are major causes of morbidity and mortality worldwide.

E-mail:
camire [at] chop.edu