Microbiome | CHOP Research Institute


Dr. Zong is an attending physician with the Division of Gastroenterology, Hepatology and Nutrition at CHOP. She specializes in clinical nutrition, intestinal rehabilitation, and enteral and parenteral nutrition. Her research focuses on the microbiome and nutrition.

zongw [at] chop.edu
Published on
Aug 31, 2022
Our featured Faculty Spotlight for August, Joseph Zackular, PhD, studies the interaction between Clostridioides difficile and microbes.

Dr. Srinivasan is an attending neonatologist with the Pediatric Sepsis Program and the Division of Neonatology at Children's Hospital of Philadelphia. Her research focuses on biomarkers in neonatal inflammation and infection; and improving prediction, recognition and management of neonatal infections.

srinivasanl [at] chop.edu

The Penn Human Intervention Core offers a wide array of services to assist with the design and implementation of microbiome studies.

The Penn Microbial Culture and Metabolomics Core features facilities and equipment for the aerobic and anaerobic culture of microbial species in both batch and continuous systems, as well targeted metabolomics services.

The goals of the Penn Acute Care Biobanking Core are to encourage and facilitate microbiome-focused research in the pathogenesis, diagnosis, and treatment of patients with critical illness.

The University of Pennsylvania launched the Penn Gnotobiotic Mouse Facility (PGMF) to aid new research in this area and provide investigators with germ-free animal models to further their research.

The Center supports the planning of microbiome projects, DNA purification, library preparation, high-throughput sequencing, and bioinformatic analysis of the output.

The MAGIC Study is looking at the microbiome as it develops during the first two years of life. It brings together expertise in the microbiome, antibiotic stewardship, immunology, neonatology, and infectious diseases to study the effect that health and environment have on the microbiome and growth.

The purpose of this study is to characterize the microbiome in children with Crohn's disease who have perianal fistula and to compare it to other children with Crohn's disease who do not have perianal disease.