Developmental Disorders | CHOP Research Institute

‘Embracing Diversity in Science:’ Q&A With Lorianna Colon, PhD, Diversity Fellow

Published on

Dec 6, 2021

A new Diversity Fellow, Dr. Colon studies early life models of neuropsychiatric disorders.

Krantz Laboratory

The Krantz lab focuses on identifying molecular etiologies of multisystem developmental diagnoses, structural birth defects, and intellectual disability. Using cellular and animal models, the investigators study newly identified genes towards identification of therapeutic targets.

Eisch Laboratory

Investigating limbic circuitry, mental function, and new neurons of the postnatal brain (Lab LMNoP).

Studying ‘The Beginning’ to Understand What Comes Later: Q&A With J. Christopher Edgar, PhD

Published on

Jan 7, 2019

in Cornerstone Blog

Infant brain imaging research aims to help future studies identify differences in brain maturation in children with developmental disabilities.

Ian D. Krantz, MD

Dr. Krantz's lab identifies and characterizes the molecular etiology of syndromic and non-syndromic developmental disorders. He has identified genes for several genetic conditions (Cornelia de Lange Syndrome, CHOPS syndrome, Alagille syndrome, hearing loss) implicating critical molecular pathways in human disorders for the first time. He has been at the forefront of studying the integration of genomics into clinical settings.

E-mail:

krantz [at] chop.edu

Amelia J. Eisch, PhD

Dr. Eisch is a neuroscientist interested in how molecular, cellular, and circuit changes—particularly in the limbic system—influence motivated behavior and cognition. She is specifically interested in how neuroplasticity in the hippocampal dentate gyrus contributes to both normal and pathological function with relevance to depression and addiction.

E-mail:

eischa [at] chop.edu