VEO-IBD | CHOP Research Institute
 

VEO-IBD

The Sullivan Lab has a broad interest in immune dysfunction. This can underlie susceptibility to infections and autoimmunity and inflammation. The investigators in the lab use cutting-edge approaches to investigate cause in individual patients and to look at population-wide causes of disease.

The Hamilton Lab studies epithelial cells in the intestine and colon and the roles they play in maintaining human health.

Generating new insights from multidisciplinary translational research to provide personalized therapy worldwide for more children with inflammatory bowel disease.

Published on
Apr 3, 2019
Marcella Devoto, PhD; Judith Kelsen, MD; and colleagues are using technologies like whole exome sequencing to uncover the genetic basis of very early onset inflammatory bowel disease.

Dr. Kelsen’s research focus is on the genetic, immunologic, and microbiomic causes of very early onset inflammatory bowel disease. Through a multidisciplinary team approach, Dr. Kelsen and her colleagues perform genetic sequencing to identify causative genetic variants in children with VEO-IBD, study the function of these variants, and use this information to improve the clinical outcomes for these children.

E-mail:
kelsen [at] chop.edu
Published on
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Published on
Sep 10, 2015
Melding together genomics technology, disease patterns, immunology, and microbiology, physician-scientists at The Children’s Hospital of Philadelphia are finding new and individualized therapies for patients with very early onset inflammatory bowel disease.