Megakaryocytes | CHOP Research Institute
 

Megakaryocytes

Marks Laboratory

Marks Lab

The Marks Lab aims to dissect the molecular mechanisms underlying the formation of cell type-specific lysosome-related organelles and the assembly, delivery, and function of their contents, and to understand how these processes are impacted by genetic diseases.

Michele Lambert, MD, MSTR
Michele Lambert

Dr. Lambert's research focuses on understanding the mechanisms of inherited and acquired thrombocytopenia in pediatric patients. Using clinical translational methods to link discovery in rare platelet disorders with optimizing next-generation sequencing for clinical practice, she has been involved in the Undiagnosed Disease Network Program and the Frontier Program in Immune Dysregulation, incorporating genetics of platelet disorders and immunohematology.

E-mail:
lambertm [at] chop.edu
Michael S. Marks, PhD
Michael S. Marks

Dr. Marks investigates the molecular mechanisms underlying the formation of cell type-specific lysosome-related organelles; the assembly, delivery and function of their contents; and how these processes are impacted by genetic diseases.

E-mail:
marksms [at] chop.edu

Diversity Makes a Difference: Q&A With Brian Estevez, PhD, New Diversity Fellow

Published on
Jan 25, 2017
in Cornerstone Blog
Brian Estevez, PhD
Looking at a scientific problem from new and different perspectives is what research is all about, which is why Children's Hospital of Philadelphia's Research Institute is dedicated to cultivating a more diverse workforce. "We value diversity within our research community and it is undoubtedly part of what makes us successful," wrote Bryan A. Wolf, MD, PhD, Chief Scientific Officer and Director

Platelet Granule Formation Gives Insight Into Rare Disease

Published on
Jul 23, 2014
in Cornerstone Blog
Cell biologists at The Children’s Hospital of Philadelphia Research Institute speculate that platelet granules hold the key to unlocking the mechanisms behind Hermansky-Pudlak syndrome.