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The study aims to determine whether evaluation of respiratory epithelial cell gene expression and protein profiling of exhaled breath condensate can identify ARDS subtypes.
Aim 1: Perform transcriptomics on samples of nasal epithelial cells obtained from brushing in children with ARDS on days 1, 3, 7, and 14 after eligibility.
Aim 2: Perform unbiased proteomic analysis on exhaled breath condensate collected from filters of subjects with ARDS who remain invasively ventilated on days 1, 3, 7, and 14 after eligibility.
Eligibility & Criteria
IRB #:
20-017205
Official Title:
Subtypes of Pediatric Acute Respiratory Distress Syndrome Using Oro-nasal Transcriptomics
Study Phase:
Not Applicable
Eligible Age Range:
0 Months - 17 Years
Gender:
All
Study Categories:
Leader