Research Discovery Finder

Children's Hospital of Philadelphia Research Institute is committed to improving the health and well-being of children in our community and across the world through advances in medicine and science. Your participation makes a difference in helping discover scientific breakthroughs and advancing care. Our research varies from innovative clinical trials to socio-behavioral research and studies you can complete from home. Check out some of our currently recruiting studies below or view past studies.

Did You Know?

Our scientists and staff aren’t the only ones who make breakthroughs happen. Many clinical trials would not succeed without patients, families, and individuals who volunteer to participate. See three little-known facts about participating in clinical research studies at Children’s Hospital of Philadelphia:

Most studies don’t involve drugs or devices. They include questionnaires, games, and learning about child development.
You don't have to travel to CHOP to participate in research. Some of our studies can be completed from home!
Knowledge gained through research helps improve the health and well-being of children in our community and around the world.

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AALL1521; Ruxolitinib and Chemotherapy for Patients with JAK-Mutant B-ALL

This study is testing the safety and effectiveness of adding a targeted therapy (ruxolitinib) to standard chemotherapy for children, adolescents, and young adults with high-risk acute lymphoblastic leukemia with CRLF2 and other JAK pathway mutations.

Related PI: Sarah K. Tasian, MD