Research Discovery Finder

Children's Hospital of Philadelphia Research Institute is committed to improving the health and well-being of children in our community and across the world through advances in medicine and science. Your participation makes a difference in helping discover scientific breakthroughs and advancing care. Our research varies from innovative clinical trials to socio-behavioral research and studies you can complete from home. Check out some of our currently recruiting studies below or view past studies.

Did You Know?

Our scientists and staff aren’t the only ones who make breakthroughs happen. Many clinical trials would not succeed without patients, families, and individuals who volunteer to participate. See three little-known facts about participating in clinical research studies at Children’s Hospital of Philadelphia:

Most studies don’t involve drugs or devices. They include questionnaires, games, and learning about child development.
You don't have to travel to CHOP to participate in research. Some of our studies can be completed from home!
Knowledge gained through research helps improve the health and well-being of children in our community and around the world.

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AALL1131; A Phase 3 Randomized Trial for HR B-ALL with Dasatinib Arm in Ph-like TKI Sensitive Mutations

The study compares 2 different experimental chemotherapy combinations with the usual chemotherapy combination given during post-Induction therapy.

Related PI: Susan R. Rheingold, MD

Related Conditions: Down Syndrome, Acute Lymphoblastic Leukemia, Leukemia, Oncology

MRI Study for Infants with Down Syndrome

The goal of this study is to increase our understanding of how the brain is affected in infants with and without Down Syndrome

Related PI: Robert T. Schultz, PhD

Related Conditions: Down Syndrome, Autism, Autism Spectrum Disorder, Imaging, MRI